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Descriptor English: Abrin
Descriptor Spanish: Abrina
Descriptor abrina
Scope note: Lectina tóxica de las semillas del regaliz americano, Abrus precatorius L. Es un veneno muy activo. Hasta la fecha se han aislado cinco proteínas diferentes: la abroaglutinina, que es el compuesto al que se debe la actividad hemaglutinante, y las abrinas a-d, que son principios tóxicos cada uno de los cuales está constituido por dos cadenas peptídicas unidas por enlaces disulfuro.
Descriptor Portuguese: Abrina
Descriptor French: Abrine
Entry term(s): Abrin A
Abrin C
Tree number(s): D08.811.277.450.430.700.750.111
D12.776.503.499.249
D12.776.765.678.906.111
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000036
Scope note: A toxic lectin from the seeds of jequirity, Abrus precatorius L. Very active poison. Five different proteins have so far been isolated: Abrus agglutinin, the component responsible for: hemagglutinating activity, & abrins a-d, the toxic principals each consisting of two peptide chains are held together by disulfide bonds.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 1393-62-0
CAS Type 1 Name: Abrins
Previous Indexing: Disulfides (1973-1974)
Plant Proteins (1971-1975)
Public MeSH Note: 91; was see under PLANT PROTEINS 1975-90
History Note: 91(75); was see under PLANT PROTEINS 1975-90
DeCS ID: 39
Unique ID: D000036
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2007/07/09
Abrin - Preferred
Concept UI M0000055
Scope note A toxic lectin from the seeds of jequirity, Abrus precatorius L. Very active poison. Five different proteins have so far been isolated: Abrus agglutinin, the component responsible for: hemagglutinating activity, & abrins a-d, the toxic principals each consisting of two peptide chains are held together by disulfide bonds.
Preferred term Abrin
Abrin C - Narrower
Concept UI M0000057
Preferred term Abrin C
Abrin A - Narrower
Concept UI M0000056
Preferred term Abrin A



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