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Descriptor English: Dihydroergotoxine
Descriptor Spanish: Dihidroergotoxina
Descriptor dihidroergotoxina
Entry term(s) alcaloides de cornezuelo hidrogenados
co-dergocrina
Scope note: Mezcla de tres diferentes derivados hidrogenados de la ERGOTAMINA: la DIHIDROERGOCORNINA; la DIHIDROERGOCRISTINA; y la DIHIDROERGOCRIPTINA. La dihiidroergotoxina se ha postulado como agente neuroprotector y agente nootrópico. El mecanismo de sus acciones terapéuticas no está claro, aunque puede actuar como un antagonista alfa-adrenérgico y agonista de la dopamina. Las sales del metanosulfonato de esta mezcla de alcaloides se denominan MESILATOS ERGOLOIDES.
Descriptor Portuguese: Di-Hidroergotoxina
Descriptor French: Dihydroergotoxine
Entry term(s): Alkaloids, Hydrogenated Ergot
Co-Dergocrine
Dihydroergotoxin
Ergot Alkaloids, Hydrogenated
Hydrogenated Ergot Alkaloids
Tree number(s): D03.132.327.412.250
D03.633.400.562.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004088
Scope note: A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Adrenergic alpha-Antagonists
Dopamine Agonists
Registry Number: 11032-41-0
CAS Type 1 Name: Ergotoxine, dihydro-
Previous Indexing: Ergot Mesylates (1973-1974)
Public MeSH Note: 1977; see ERGOT ALKALOIDS HYDROGENATED 1975-1976; for ERGOT ALKALOIDS, HYDROGENATED see ERGOLOID MESYLATES 1992-2001
History Note: 1977(1975); for ERGOT ALKALOIDS, HYDROGENATED use ERGOLOID MESYLATES 1992-2001
Related: Dihydroergocornine MeSH
Dihydroergocristine MeSH
Dihydroergocryptine MeSH
DeCS ID: 4128
Unique ID: D004088
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1977/01/01
Date of Entry: 1974/11/27
Revision Date: 2016/05/31
Dihydroergotoxine - Preferred
Concept UI M0006406
Scope note A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES.
Preferred term Dihydroergotoxine
Entry term(s) Co-Dergocrine
Dihydroergotoxin
Ergot Alkaloids, Hydrogenated - Broader
Concept UI M0374754
Preferred term Ergot Alkaloids, Hydrogenated
Entry term(s) Alkaloids, Hydrogenated Ergot
Hydrogenated Ergot Alkaloids



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