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Descriptor English: 5,6-Dihydroxytryptamine
Descriptor Spanish: 5,6-Dihidroxitriptamina
Descriptor 5,6-dihidroxitriptamina
Scope note: Triptamina sustituida con dos grupos hidroxilo en las posiciones 5 y 6. Es un análogo neurotóxico de la serotonina, que destruye preferentemente las neuronas serotoninérgicas y se utiliza en investigación neurofarmacológica.
Descriptor Portuguese: 5,6-Di-Hidroxitriptamina
Descriptor French: Dihydroxy-5,6 tryptamine
Entry term(s): 3-(2-Aminoethyl)indole-5,6-diol
5,6 Dihydroxytryptamine
Tree number(s): D03.633.100.473.914.201.259
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015115
Scope note: Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Serotonin Agents
Registry Number: W2QY253O8S
CAS Type 1 Name: 1H-Indole-5,6-diol, 3-(2-aminoethyl)-
Previous Indexing: Tryptamines (1966-1974)
Public MeSH Note: 78; was see under TRYPTAMINES 1975-77
History Note: 78(75); was see under TRYPTAMINES 1975-77
DeCS ID: 4141
Unique ID: D015115
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1974/11/27
Revision Date: 2016/05/27
5,6-Dihydroxytryptamine - Preferred
Concept UI M0023255
Scope note Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research.
Preferred term 5,6-Dihydroxytryptamine
Entry term(s) 3-(2-Aminoethyl)indole-5,6-diol
5,6 Dihydroxytryptamine



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