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Descriptor English: 5,7-Dihydroxytryptamine
Descriptor Spanish: 5,7-Dihidroxitriptamina
Descriptor 5,7-dihidroxitriptamina
Scope note: Triptamina sustituida con dos gruos hidroxilo en las posiciones 5 y 7. Es un análogo neurotóxico de la serotonina, que destruye preferentementes las neuronas serotoninérgicas y se utiliza en investigación neurofarmacológica.
Descriptor Portuguese: 5,7-Di-Hidroxitriptamina
Descriptor French: Dihydroxy-5,7 tryptamine
Entry term(s): 3-(2-Aminoethyl)-1H-indole-5,7-diol
5,7 Dihydroxytryptamine
5,7 Dihydroxytryptamine Creatine Sulfate
5,7-Dihydroxytryptamine Creatine Sulfate
Creatine Sulfate, 5,7-Dihydroxytryptamine
Sulfate, 5,7-Dihydroxytryptamine Creatine
Tree number(s): D03.633.100.473.914.201.263
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015116
Scope note: Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Serotonin Agents
Registry Number: 31363-74-3
CAS Type 1 Name: 1H-Indole-5,7-diol, 3-(2-aminoethyl)-
Previous Indexing: Tryptamines (1966-1977)
Public MeSH Note: 91; was see under DIHYDROXYTRYPTAMINES 1978-90
History Note: 91(78); was see under DIHYDROXYTRYPTAMINES 1978-90
DeCS ID: 4143
Unique ID: D015116
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/27
Revision Date: 2016/05/27
5,7-Dihydroxytryptamine - Preferred
Concept UI M0023256
Scope note Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool.
Preferred term 5,7-Dihydroxytryptamine
Entry term(s) 3-(2-Aminoethyl)-1H-indole-5,7-diol
5,7 Dihydroxytryptamine
5,7-Dihydroxytryptamine Creatine Sulfate - Narrower
Concept UI M0023257
Preferred term 5,7-Dihydroxytryptamine Creatine Sulfate
Entry term(s) 5,7 Dihydroxytryptamine Creatine Sulfate
Creatine Sulfate, 5,7-Dihydroxytryptamine
Sulfate, 5,7-Dihydroxytryptamine Creatine



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