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Descriptor English: Dimethyl Adipimidate
Descriptor Spanish: Dimetil Adipimidato
Descriptor dimetil adipimidato
Entry term(s) dimetil adipimato
dimetil adipinamidato
Scope note: Agente bifuncional de enlaces cruzados que de modo covalente une grupos amino libres de proteínas o polipéptidos, incluidos los que se encuentran en las membranas celulares. Se utiliza como reactivo o fijador en inmunohistoquímica y se ha propuesto como agente antidrepanocitario.
Descriptor Portuguese: Dimetil Adipimidato
Descriptor French: Adipimidate de diméthyle
Entry term(s): Adipimate, Dimethyl
Adipimidate, Dimethyl
Adipinamidate, Dimethyl
Dimethyl Adipimate
Dimethyl Adipinamidate
Tree number(s): D02.241.081.337.052.250
D02.478.400.175
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004119
Scope note: Bifunctional cross-linking agent that links covalently free amino groups of proteins or polypeptides, including those in cell membranes. It is used as reagent or fixative in immunohistochemistry and is a proposed antisickling agent.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antisickling Agents
Indicators and Reagents
Registry Number: 13139-70-3
CAS Type 1 Name: Hexanediimidic acid, dimethyl ester
Previous Indexing: Adipic Acids (1966-1977)
Imides (1966-1977)
Public MeSH Note: 91; was see under IMIDOESTERS 1980-90; was see under IMIDES 1978-79
History Note: 91(78); was see under IMIDOESTERS 1980-90; was see under IMIDES 1978-79
DeCS ID: 4167
Unique ID: D004119
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/22
Revision Date: 2000/06/21
Dimethyl Adipimidate - Preferred
Concept UI M0006454
Scope note Bifunctional cross-linking agent that links covalently free amino groups of proteins or polypeptides, including those in cell membranes. It is used as reagent or fixative in immunohistochemistry and is a proposed antisickling agent.
Preferred term Dimethyl Adipimidate
Entry term(s) Adipimate, Dimethyl
Adipimidate, Dimethyl
Adipinamidate, Dimethyl
Dimethyl Adipimate
Dimethyl Adipinamidate



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