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Descriptor English: Dithionitrobenzoic Acid
Descriptor Spanish: Ácido Ditionitrobenzoico
Descriptor ácido ditionitrobenzoico
Entry term(s) 5,5'-ditiobis(2-ácido nitrobenzoico)
DTNB
reactivo de Ellman
Scope note: Reactivo estándar para la determinación de grupos sulfhidrilo reactivos por determinaciones de absorbancia. Se utiliza principalmente para la determinación de grupos sulfhidrilo y disulfuro en las proteínas. El color producido se debe a la formación de un anión tio, 3-carboxilo-4-nitrotiofenolato.
Descriptor Portuguese: Ácido Ditionitrobenzoico
Descriptor French: 5,5'-Dithiobis(acide 2-nitro-benzoïque)
Entry term(s): 5,5'-Dithiobis(2-nitrobenzoic Acid)
5,5'-Dithiobis(nitrobenzoate)
Acid, Dithionitrobenzoic
DTNB
Ellman Reagent
Ellman's Reagent
Ellmans Reagent
Reagent, Ellman's
Tree number(s): D02.241.223.100.600.300
D02.455.426.559.389.127.650.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004228
Scope note: A standard reagent for the determination of reactive sulfhydryl groups by absorbance measurements. It is used primarily for the determination of sulfhydryl and disulfide groups in proteins. The color produced is due to the formation of a thio anion, 3-carboxyl-4-nitrothiophenolate.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Sulfhydryl Reagents
Registry Number: 9BZQ3U62JX
CAS Type 1 Name: Benzoic acid, 3,3'-dithiobis(6-nitro)-
Previous Indexing: Benzoates (1969-1974)
Disulfides (1972-1974)
Nitro Compounds (1972-1974)
Public MeSH Note: 91; was see under NITROBENZOATES 1975-90
History Note: 91(75); was see under NITROBENZOATES 1975-90
DeCS ID: 4290
Unique ID: D004228
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/14
Revision Date: 2013/07/08
Dithionitrobenzoic Acid - Preferred
Concept UI M0006618
Scope note A standard reagent for the determination of reactive sulfhydryl groups by absorbance measurements. It is used primarily for the determination of sulfhydryl and disulfide groups in proteins. The color produced is due to the formation of a thio anion, 3-carboxyl-4-nitrothiophenolate.
Preferred term Dithionitrobenzoic Acid
Entry term(s) 5,5'-Dithiobis(2-nitrobenzoic Acid)
Acid, Dithionitrobenzoic
DTNB
Ellman Reagent
Ellman's Reagent
Ellmans Reagent
Reagent, Ellman's
5,5'-Dithiobis(nitrobenzoate) - Narrower
Concept UI M0006620
Preferred term 5,5'-Dithiobis(nitrobenzoate)



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