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Descriptor English: Allylisopropylacetamide
Descriptor Spanish: Alilisopropilacetamida
Descriptor alilisopropilacetamida
Scope note: Compuesto alílico que actua como inactivador suicida del CITOCROMO P450 mediante unión covalente a su parte hemo o proteína circundante.
Descriptor Portuguese: Alilisopropilacetamida
Descriptor French: 2-Isopropyl-pent-4-énamide
Entry term(s): 2 Isopropyl 4 Pentenamide
2-Isopropyl-4-Pentenamide
Tree number(s): D02.065.064.189
D02.241.081.018.110.189
D02.455.326.271.122.272
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000502
Scope note: An allylic compound that acts as a suicide inactivator of CYTOCHROME P450 by covalently binding to its heme moiety or surrounding protein.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 299-78-5
CAS Type 1 Name: 4-Pentenamide, 2-(1-methylethyl)-
Public MeSH Note: 91; was see under ACETAMIDES 1973-90
History Note: 91(73); was see under ACETAMIDES 1973-90
DeCS ID: 505
Unique ID: D000502
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2012/07/03
Allylisopropylacetamide - Preferred
Concept UI M0000754
Scope note An allylic compound that acts as a suicide inactivator of CYTOCHROME P450 by covalently binding to its heme moiety or surrounding protein.
Preferred term Allylisopropylacetamide
Entry term(s) 2 Isopropyl 4 Pentenamide
2-Isopropyl-4-Pentenamide



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