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Descriptor English: Lacosamide
Descriptor Spanish: Lacosamida
Descriptor lacosamida
Entry term(s) N benzil 2 acetamido 3 metoxipropionamida
N benzil AcMeOPrNH2
N-benzil-2-acetamido-3-metoxipropionamida
N-benzil-AcMeOPrNH2
Vimpat
Scope note: Derivado de acetamida que actúa como bloqueador de los CANALES DEL SODIO DEPENDIENTES DE VOLTAJE. Se usa como anticonvulsivante, en forma de terapia complementaria o de monoterapia, en el tratamiento de las EPILEPSIAS PARCIALES.
Descriptor Portuguese: Lacosamida
Descriptor French: Lacosamide
Entry term(s): N benzyl 2 acetamido 3 methoxypropionamide
N benzyl AcMeOPrNH2
N-benzyl-2-acetamido-3-methoxypropionamide
N-benzyl-AcMeOPrNH2
Vimpat
Tree number(s): D02.065.064.416
D02.241.081.018.110.432
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000078334
Scope note: An acetamide derivative that acts as a blocker of VOLTAGE-GATED SODIUM CHANNELS. It is used as an anticonvulsant, for adjunctive or monotherapy, in the treatment of PARTIAL SEIZURES.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticonvulsants
Voltage-Gated Sodium Channel Blockers
Registry Number: 563KS2PQY5
CAS Type 1 Name: Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-
Public MeSH Note: 2019; LACOSAMIDE was indexed under ACETAMIDES 2000-2019
History Note: 2019 (2000)
DeCS ID: 57809
Unique ID: D000078334
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/05/21
Lacosamide - Preferred
Concept UI M0356576
Scope note An acetamide derivative that acts as a blocker of VOLTAGE-GATED SODIUM CHANNELS. It is used as an anticonvulsant, for adjunctive or monotherapy, in the treatment of PARTIAL SEIZURES.
Preferred term Lacosamide
Vimpat - Narrower
Concept UI M0540932
Preferred term Vimpat
N-benzyl-2-acetamido-3-methoxypropionamide - Related but not broader or narrower
Concept UI M000642505
Preferred term N-benzyl-2-acetamido-3-methoxypropionamide
Entry term(s) N benzyl 2 acetamido 3 methoxypropionamide
N benzyl AcMeOPrNH2
N-benzyl-AcMeOPrNH2



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