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Descriptor English: Glycine Dehydrogenase (Decarboxylating)
Descriptor Spanish: Glicina-Deshidrogenasa (Descarboxilante)
Descriptor glicina deshidrogenasa (descarboxilante)
Entry term(s) glicina-dehidrogenasa (descarboxilante)
glicina-deshidrogenasa (descarboxilante)
Scope note: Enzima dependiente del FOSFATO DE PIRIDOXAL que cataliza la descarboxilación de la GLICINA con transferencia de un grupo aminometilo a la porción de ÁCIDO LIPOICO de la PROTEÍNA H DEL COMPLEJO DE LA GLICINA-DESCARBOXILASA. Los defectos de la proteína P son la causa de la hiperglicinemia no cetósica. Es una de las cuatro subunidades del complejo de la glicina-descarboxilasa.
Descriptor Portuguese: Glicina Desidrogenase (Descarboxilante)
Descriptor French: Glycine dehydrogenase (decarboxylating)
Entry term(s): Decarboxylase P-protein, Glycine
Decarboxylase, Glycine
Glycine Cleavage System P Protein
Glycine Cleavage System P-Protein
Glycine Decarboxylase
Glycine Decarboxylase Complex P Protein
Glycine Decarboxylase Complex P-Protein
Glycine Decarboxylase P-protein
P protein, Glycine Decarboxylase
P-protein, Glycine Decarboxylase
Tree number(s): D05.500.562.452.200
D08.811.600.391.200
D08.811.682.664.500.498.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050841
Scope note: A PYRIDOXAL PHOSPHATE dependent enzyme that catalyzes the decarboxylation of GLYCINE with the transfer of an aminomethyl group to the LIPOIC ACID moiety of the GLYCINE DECARBOXYLASE COMPLEX H-PROTEIN. Defects in P-protein are the cause of non-ketotic hyperglycinemia. It is one of four subunits of the glycine decarboxylase complex.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.4.4.2
Public MeSH Note: 2006; GLYCINE DEHYDROGENASE (DECARBOXYLATING) was indexed under AMINO ACID OXIDOREDUCTASES 1990-2005
History Note: 2006
DeCS ID: 50549
Unique ID: D050841
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Glycine Dehydrogenase (Decarboxylating) - Preferred
Concept UI M0177687
Scope note A PYRIDOXAL PHOSPHATE dependent enzyme that catalyzes the decarboxylation of GLYCINE with the transfer of an aminomethyl group to the LIPOIC ACID moiety of the GLYCINE DECARBOXYLASE COMPLEX H-PROTEIN. Defects in P-protein are the cause of non-ketotic hyperglycinemia. It is one of four subunits of the glycine decarboxylase complex.
Preferred term Glycine Dehydrogenase (Decarboxylating)
Entry term(s) Decarboxylase P-protein, Glycine
Decarboxylase, Glycine
Glycine Cleavage System P Protein
Glycine Cleavage System P-Protein
Glycine Decarboxylase
Glycine Decarboxylase Complex P Protein
Glycine Decarboxylase Complex P-Protein
Glycine Decarboxylase P-protein
P protein, Glycine Decarboxylase
P-protein, Glycine Decarboxylase



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