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Descriptor English: Ethacrynic Acid
Descriptor Spanish: Ácido Etacrínico
Descriptor ácido etacrínico
Scope note: Compuesto que inhibe el simporte de sodio, potasio y cloruro principalmente en el asa de Henle ascendente, pero también en los túbulos proximales y distales. Esta acción farmacológica da lugar a la excreción de estos iones, aumento de la diuresis y reducción en el líquido extracelular. Se ha clasificado este compuesto como diurético de asa o de alto techo.
Descriptor Portuguese: Ácido Etacrínico
Descriptor French: Acide étacrynique
Entry term(s): Acid, Etacrynic
Acid, Ethacrinic
Acid, Ethacrynic
Edecrin
Etacrynic Acid
Ethacrinic Acid
Ethacrynate Sodium
Ethacrynic Acid, Sodium Salt
Hydromedin
Sodium, Ethacrynate
Tree number(s): D02.241.081.018.386.682.300
D02.241.511.316.682.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004976
Scope note: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Diuretics
Enzyme Inhibitors
Registry Number: M5DP350VZV
CAS Type 1 Name: Acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-
Public MeSH Note: 66
History Note: 66(63)
DeCS ID: 5068
Unique ID: D004976
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Ethacrynic Acid - Preferred
Concept UI M0007812
Scope note A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
Preferred term Ethacrynic Acid
Entry term(s) Acid, Etacrynic
Acid, Ethacrinic
Acid, Ethacrynic
Etacrynic Acid
Ethacrinic Acid
Hydromedin - Narrower
Concept UI M0351755
Preferred term Hydromedin
Edecrin - Narrower
Concept UI M0007813
Preferred term Edecrin
Ethacrynate Sodium - Narrower
Concept UI M0330353
Preferred term Ethacrynate Sodium
Entry term(s) Ethacrynic Acid, Sodium Salt
Sodium, Ethacrynate



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