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Descriptor English: bcl-2-Associated X Protein
Descriptor Spanish: Proteína X Asociada a bcl-2
Descriptor proteína X asociada a bcl-2
Entry term(s) proteína bax
proteína bax-alfa
proteína bax-omega
proteína bax-sigma
Scope note: Miembro de la familia de proteínas Bcl-2 y homólogo de la PROTEÍNA PROTOONCOGÉNICA C-BCL-2. Regula la liberación de CITOCROMO C y del FACTOR INDUCTOR DE LA APOPTOSIS de las mitocondrias. Se dan varias isoformas de la proteína X asociada a BCL-2 debido al EMPALME ALTERNATIVO del ARNm en relación con esta proteína.
Descriptor Portuguese: Proteína X Associada a bcl-2
Descriptor French: Protéine Bax
Entry term(s): Bax Apoptosis Regulator Protein
Bax Protein
Bax alpha Protein
Bax beta Protein
Bax delta Protein
Bax omega Protein
Bax sigma Protein
Bax-alpha Protein
Bax-beta Protein
Bax-delta Protein
Bax-omega Protein
Bax-sigma Protein
Protein, bcl-2-Associated X
X Protein, bcl-2-Associated
bcl 2 Associated X Protein
bcl2 Associated X Protein
bcl2 Associated X Protein Isoform alpha
bcl2 Associated X Protein Isoform beta
bcl2 Associated X Protein Isoform delta
bcl2 Associated X Protein Isoform omega
bcl2 Associated X Protein Isoform sigma
bcl2-Associated X Protein
bcl2-Associated X Protein Isoform alpha
bcl2-Associated X Protein Isoform beta
bcl2-Associated X Protein Isoform delta
bcl2-Associated X Protein Isoform omega
bcl2-Associated X Protein Isoform sigma
Tree number(s): D12.644.360.075.718.400
D12.776.476.075.718.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051028
Scope note: A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.
Annotation: Don't confuse with the closely related BCL-X PROTEIN
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; BCL2-ASSOCIATED X-PROTEIN was indexed under PROTO-ONCOGENE PROTEINS C-BCL-2 1993-2005
History Note: 2006(1993)
DeCS ID: 50806
Unique ID: D051028
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/07/06
Revision Date: 2015/11/23
bcl-2-Associated X Protein - Preferred
Concept UI M0220651
Scope note A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.
Preferred term bcl-2-Associated X Protein
Entry term(s) Bax Apoptosis Regulator Protein
Bax Protein
Protein, bcl-2-Associated X
X Protein, bcl-2-Associated
bcl 2 Associated X Protein
bcl2 Associated X Protein
bcl2-Associated X Protein
bcl2-Associated X Protein Isoform beta - Narrower
Concept UI M0480106
Preferred term bcl2-Associated X Protein Isoform beta
Entry term(s) Bax beta Protein
Bax-beta Protein
bcl2 Associated X Protein Isoform beta
bcl2-Associated X Protein Isoform sigma - Narrower
Concept UI M0479009
Preferred term bcl2-Associated X Protein Isoform sigma
Entry term(s) Bax sigma Protein
Bax-sigma Protein
bcl2 Associated X Protein Isoform sigma
bcl2-Associated X Protein Isoform omega - Narrower
Concept UI M0410933
Preferred term bcl2-Associated X Protein Isoform omega
Entry term(s) Bax omega Protein
Bax-omega Protein
bcl2 Associated X Protein Isoform omega
bcl2-Associated X Protein Isoform alpha - Narrower
Concept UI M0479012
Preferred term bcl2-Associated X Protein Isoform alpha
Entry term(s) Bax alpha Protein
Bax-alpha Protein
bcl2 Associated X Protein Isoform alpha
bcl2-Associated X Protein Isoform delta - Narrower
Concept UI M0479011
Preferred term bcl2-Associated X Protein Isoform delta
Entry term(s) Bax delta Protein
Bax-delta Protein
bcl2 Associated X Protein Isoform delta



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