| Descriptor English: | bcl-2-Associated X Protein | ||||||
| Descriptor Spanish: |
Proteína X Asociada a bcl-2
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| Descriptor Portuguese: | Proteína X Associada a bcl-2 | ||||||
| Descriptor French: | Protéine Bax | ||||||
| Entry term(s): |
Bax Apoptosis Regulator Protein Bax Protein Bax alpha Protein Bax beta Protein Bax delta Protein Bax omega Protein Bax sigma Protein Bax-alpha Protein Bax-beta Protein Bax-delta Protein Bax-omega Protein Bax-sigma Protein Protein, bcl-2-Associated X X Protein, bcl-2-Associated bcl 2 Associated X Protein bcl2 Associated X Protein bcl2 Associated X Protein Isoform alpha bcl2 Associated X Protein Isoform beta bcl2 Associated X Protein Isoform delta bcl2 Associated X Protein Isoform omega bcl2 Associated X Protein Isoform sigma bcl2-Associated X Protein bcl2-Associated X Protein Isoform alpha bcl2-Associated X Protein Isoform beta bcl2-Associated X Protein Isoform delta bcl2-Associated X Protein Isoform omega bcl2-Associated X Protein Isoform sigma |
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| Tree number(s): |
D12.644.360.075.718.400 D12.776.476.075.718.400 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051028 | ||||||
| Scope note: | A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein. |
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| Annotation: | Don't confuse with the closely related BCL-X PROTEIN |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2006; BCL2-ASSOCIATED X-PROTEIN was indexed under PROTO-ONCOGENE PROTEINS C-BCL-2 1993-2005 |
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| History Note: | 2006(1993) |
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| DeCS ID: | 50806 | ||||||
| Unique ID: | D051028 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/07/06 | ||||||
| Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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bcl-2-Associated X Protein
- Preferred
bcl2-Associated X Protein Isoform beta
- Narrower
bcl2-Associated X Protein Isoform sigma
- Narrower
bcl2-Associated X Protein Isoform omega
- Narrower
bcl2-Associated X Protein Isoform alpha
- Narrower
bcl2-Associated X Protein Isoform delta
- Narrower
| Concept UI |
M0220651 |
| Scope note | A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein. |
| Preferred term | bcl-2-Associated X Protein |
| Entry term(s) |
Bax Apoptosis Regulator Protein Bax Protein Protein, bcl-2-Associated X X Protein, bcl-2-Associated bcl 2 Associated X Protein bcl2 Associated X Protein bcl2-Associated X Protein |
| Concept UI |
M0480106 |
| Preferred term | bcl2-Associated X Protein Isoform beta |
| Entry term(s) |
Bax beta Protein Bax-beta Protein bcl2 Associated X Protein Isoform beta |
| Concept UI |
M0479009 |
| Preferred term | bcl2-Associated X Protein Isoform sigma |
| Entry term(s) |
Bax sigma Protein Bax-sigma Protein bcl2 Associated X Protein Isoform sigma |
| Concept UI |
M0410933 |
| Preferred term | bcl2-Associated X Protein Isoform omega |
| Entry term(s) |
Bax omega Protein Bax-omega Protein bcl2 Associated X Protein Isoform omega |
| Concept UI |
M0479012 |
| Preferred term | bcl2-Associated X Protein Isoform alpha |
| Entry term(s) |
Bax alpha Protein Bax-alpha Protein bcl2 Associated X Protein Isoform alpha |
| Concept UI |
M0479011 |
| Preferred term | bcl2-Associated X Protein Isoform delta |
| Entry term(s) |
Bax delta Protein Bax-delta Protein bcl2 Associated X Protein Isoform delta |
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