| Descriptor English: | Myeloid Cell Leukemia Sequence 1 Protein | ||||||
| Descriptor Spanish: |
Proteína 1 de la Secuencia de Leucemia de Células Mieloides
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| Descriptor Portuguese: | Proteína de Sequência 1 de Leucemia de Células Mieloides | ||||||
| Descriptor French: | Protéine Mcl-1 | ||||||
| Entry term(s): |
Cell Factor-1, Myeloid Factor-1, Myeloid Cell Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 Myeloid Cell Factor 1 Myeloid Cell Factor-1 Myeloid Cell Leukemia Sequence 1 |
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| Tree number(s): |
D12.644.360.075.718.984 D12.776.476.075.718.968 D12.776.624.664.700.169.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D064549 | ||||||
| Scope note: | A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2014; was indexed under NEOPLASM PROTEINS 1993-2008, and PROTO-ONCOGENE PROTEINS C-BCL-2 2009-2013 |
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| History Note: | 2014 |
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| DeCS ID: | 55309 | ||||||
| Unique ID: | D064549 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2014/01/01 | ||||||
| Date of Entry: | 2013/07/08 | ||||||
| Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Myeloid Cell Leukemia Sequence 1 Protein
- Preferred
| Concept UI |
M0215606 |
| Scope note | A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation. |
| Preferred term | Myeloid Cell Leukemia Sequence 1 Protein |
| Entry term(s) |
Cell Factor-1, Myeloid Factor-1, Myeloid Cell Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1 Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 Myeloid Cell Factor 1 Myeloid Cell Factor-1 Myeloid Cell Leukemia Sequence 1 |
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