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Descriptor English: Complement C2a
Descriptor Spanish: Complemento C2a
Descriptor complemento C2a
Scope note: El fragmento COOH-terminal del COMPLEMENTO 2, liberado por la acción del COMPLEMENTO C1S activado. Es una SERINA PROTEASA. El C2a se combina con el COMPLEMENTO C4B para formar C4b2a (CONVERTASA C3 DE LA VÍA CLÁSICA) y posterior C4b2a3b(CONVERTASA C5 DE LA VÍA CLÁSICA).
Descriptor Portuguese: Complemento C2a
Descriptor French: Complément C2a
Entry term(s): C2a Complement
C2a Fragment, Complement
C2a, Complement
Complement 2a
Complement C2 Fragment a
Complement C2a Fragment
Complement, C2a
Tree number(s): D12.776.124.486.274.150.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050678
Scope note: The COOH-terminal fragment of COMPLEMENT 2, released by the action of activated COMPLEMENT C1S. It is a SERINE PROTEASE. C2a combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Registry Number: EC 3.4.21.43
Public MeSH Note: 2006; COMPLEMENT C2A was indexed under COMPLEMENT 2 1986-2005
History Note: 2006 (1986)
DeCS ID: 50825
Unique ID: D050678
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Complement C2a - Preferred
Concept UI M0138655
Scope note The COOH-terminal fragment of COMPLEMENT 2, released by the action of activated COMPLEMENT C1S. It is a SERINE PROTEASE. C2a combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
Preferred term Complement C2a
Entry term(s) C2a Complement
C2a Fragment, Complement
C2a, Complement
Complement 2a
Complement C2 Fragment a
Complement C2a Fragment
Complement, C2a



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