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Descriptor English: Complement C3 Convertase, Classical Pathway
Descriptor Spanish: C3 Convertasa de la Vía Clásica del Complemento
Descriptor convertasa del complemento C3 de la vía clásica
Scope note: Serina proteasa que desdobla el COMPLEMENTO C3 múltiple en COMPLEMENTO 3A (anafilotoxina) y el COMPLEMENTO 3B en la VÍA CLÁSICA DE ACTIVACIÓN DEL COMPLEMENTO. Es un complejo del COMPLEMENTO 4B y del COMPLEMENTO 2A (C4b2a).
Descriptor Portuguese: C3 Convertase da Via Clássica do Complemento
Descriptor French: Classical pathway complement C3 convertase
Entry term(s): C3 Convertase (C4b2a)
C3 Convertase, Classical
Classical C3 Convertase
Classical Pathway C3 Convertase
Tree number(s): D12.776.124.486.274.045.387.750.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051574
Scope note: A serine protease that cleaves multiple COMPLEMENT 3 into COMPLEMENT 3A (anaphylatoxin) and COMPLEMENT 3B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of COMPLEMENT 4B and COMPLEMENT 2A (C4b2a).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Registry Number: EC 3.4.21.43
Previous Indexing: Complement C3-C5 Convertases (1979-2005)
Complement Pathway, Classical (1980-2005)
Public MeSH Note: 2006
History Note: 2006
DeCS ID: 50833
Unique ID: D051574
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2006/07/05
Complement C3 Convertase, Classical Pathway - Preferred
Concept UI M0476526
Scope note A serine protease that cleaves multiple COMPLEMENT 3 into COMPLEMENT 3A (anaphylatoxin) and COMPLEMENT 3B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of COMPLEMENT 4B and COMPLEMENT 2A (C4b2a).
Preferred term Complement C3 Convertase, Classical Pathway
Entry term(s) C3 Convertase (C4b2a)
C3 Convertase, Classical
Classical C3 Convertase
Classical Pathway C3 Convertase



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