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Descriptor English: Complement C5 Convertase, Classical Pathway
Descriptor Spanish: C5 Convertasa de la Vía Clásica del Complemento
Descriptor convertasa del complemento C5 de la vía clásica
Scope note: Serina proteasa que desdobla el COMPLEMENTO 5 múltiple en COMPLEMENTO 5A (anafilotoxina) y COMPLEMENTO 5B en la VÍA CLÁSICA DE ACTIVACIÓN DEL COMPLEMENTO. Es un complejo de la CONVERTASA C3 DE LA VIA CLÁSICA (C4b2a) con un COMPLEMENTO C3B, o C4b2a3b, adicional.
Descriptor Portuguese: C5 Convertase da Via Clássica do Complemento
Descriptor French: Classical pathway C5 convertase
Entry term(s): C5 Convertase (C4b2a3b)
C5 Convertase, Classical
Classical C5 Convertase
Classical Pathway C5 Convertase
Tree number(s): D12.776.124.486.274.045.387.750.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051577
Scope note: A serine protease that cleaves multiple COMPLEMENT 5 into COMPLEMENT 5A (anaphylatoxin) and COMPLEMENT 5B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of CLASSICAL PATHWAY C3 CONVERTASE (C4b2a) with an additional COMPLEMENT C3B, or C4b2a3b.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Registry Number: EC 3.4.21.43
Previous Indexing: Complement Activating Enzymes (1983-2005)
Complement Pathway, Classical (1983-2005)
Public MeSH Note: 2006
History Note: 2006
DeCS ID: 50834
Unique ID: D051577
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2006/07/05
Complement C5 Convertase, Classical Pathway - Preferred
Concept UI M0476527
Scope note A serine protease that cleaves multiple COMPLEMENT 5 into COMPLEMENT 5A (anaphylatoxin) and COMPLEMENT 5B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of CLASSICAL PATHWAY C3 CONVERTASE (C4b2a) with an additional COMPLEMENT C3B, or C4b2a3b.
Preferred term Complement C5 Convertase, Classical Pathway
Entry term(s) C5 Convertase (C4b2a3b)
C5 Convertase, Classical
Classical C5 Convertase
Classical Pathway C5 Convertase



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