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Descriptor English: Early Growth Response Protein 2
Descriptor Spanish: Proteína 2 de la Respuesta de Crecimiento Precoz
Descriptor proteína 2 de respuesta del crecimiento precoz
Scope note: Factor de transcripción de la respuesta de crecimiento precoz que controla la formación de la VAINA DE MIELINA alrededor de los AXONES periféricos por las CÉLULAS DE SCHWANN. Las mutaciones del factor de transcripción EGR2 se han asociado con NEUROPATÍAS SENSORIALES Y MOTORAS HEREDITARIAS, como la ENFERMEDAD DE CHARCOT-MARIE-TOOTH.
Descriptor Portuguese: Proteína 2 de Resposta de Crescimento Precoce
Descriptor French: Facteur de transcription EGR-2
Entry term(s): EGR2 Transcription Factor
Krox 20 Transcription Factor
Krox-20 Transcription Factor
Krox20 Protein
Transcription Factor, EGR2
Transcription Factor, Krox-20
Tree number(s): D12.776.260.158.750
D12.776.460.525.750
D12.776.930.213.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051767
Scope note: An early growth response transcription factor that controls the formation of the MYELIN SHEATH around peripheral AXONS by SCHWANN CELLS. Mutations in EGR2 transcription factor have been associated with HEREDITARY MOTOR AND SENSORY NEUROPATHIES such as CHARCOT-MARIE-TOOTH DISEASE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; EARLY GROWTH RESPONSE PROTEIN 2 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1988-2005
History Note: 2006(1988)
Related: Charcot-Marie-Tooth Disease MeSH
DeCS ID: 50983
Unique ID: D051767
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/05/27
Early Growth Response Protein 2 - Preferred
Concept UI M0158412
Scope note An early growth response transcription factor that controls the formation of the MYELIN SHEATH around peripheral AXONS by SCHWANN CELLS. Mutations in EGR2 transcription factor have been associated with HEREDITARY MOTOR AND SENSORY NEUROPATHIES such as CHARCOT-MARIE-TOOTH DISEASE.
Preferred term Early Growth Response Protein 2
Entry term(s) EGR2 Transcription Factor
Krox 20 Transcription Factor
Krox-20 Transcription Factor
Krox20 Protein
Transcription Factor, EGR2
Transcription Factor, Krox-20



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