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Descriptor English: Immediate-Early Proteins
Descriptor Spanish: Proteínas Inmediatas-Precoces
Descriptor Portuguese: Proteínas Imediatamente Precoces
Descriptor French: Protéines précoces immédiates
Entry term(s): Immediate Early Proteins
Proteins, Immediate Early
Proteins, Immediate-Early
Tree number(s): D12.776.460
D12.776.964.925.968
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017874
Scope note: Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.
Annotation: proteins coded by immed-early genes: read MeSH definition for history of "immediate-early"
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Viral Proteins (1974-1993)
Public MeSH Note: 94
History Note: 94
DeCS ID: 31394
Unique ID: D017874
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1992/12/28
Revision Date: 2007/07/09
Immediate-Early Proteins - Preferred
Concept UI M0027006
Scope note Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.
Preferred term Immediate-Early Proteins
Entry term(s) Immediate Early Proteins
Proteins, Immediate Early
Proteins, Immediate-Early



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