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Descriptor English: GATA3 Transcription Factor
Descriptor Spanish: Factor de Transcripción GATA3
Descriptor factor de transcripción GATA3
Scope note: Factor de transcripción GATA que se encuentra principalmente en los precursores de las CÉLULAS LINFOIDES y que se ha relacionado con el proceso de DIFERENCIACIÓN CELULAR de los LINFOCITOS T COOPERADORES. La haploinsuficiencia de GATA3 se asocia a HIPOPARATIROIDISMO, HIPOACUSIA NEUROSENSORIAL y síndrome de anomalías renales.
Descriptor Portuguese: Fator de Transcrição GATA3
Descriptor French: Facteur de transcription GATA-3
Entry term(s): GATA 3 Factors
GATA-3 Factors
GATA3, Transcription Factor
NF E1C Protein
NF-E1C Protein
Nuclear Factor Erythroid 1C
Nuclear Factor-Erythroid 1C
Transcription Factor GATA3
Transcription Factor, GATA3
Tree number(s): D12.776.260.235.687
D12.776.260.257.300
D12.776.930.216.687
D12.776.930.314.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050990
Scope note: A GATA transcription factor that is found predominately in LYMPHOID CELL precursors and has been implicated in the CELL DIFFERENTIATION of HELPER T-CELLS. Haploinsufficiency of GATA3 is associated with HYPOPARATHYROIDISM; SENSORINEURAL HEARING LOSS; and renal anomalies syndrome.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; GATA3 TRANSCRIPTION FACTOR was indexed under DNA-BINDING PROTEINS & TRANS-ACTIVATORS 1991-2005
History Note: 2006(1991)
DeCS ID: 50988
Unique ID: D050990
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/06/30
GATA3 Transcription Factor - Preferred
Concept UI M0187089
Scope note A GATA transcription factor that is found predominately in LYMPHOID CELL precursors and has been implicated in the CELL DIFFERENTIATION of HELPER T-CELLS. Haploinsufficiency of GATA3 is associated with HYPOPARATHYROIDISM; SENSORINEURAL HEARING LOSS; and renal anomalies syndrome.
Preferred term GATA3 Transcription Factor
Entry term(s) GATA 3 Factors
GATA-3 Factors
GATA3, Transcription Factor
NF E1C Protein
NF-E1C Protein
Nuclear Factor Erythroid 1C
Nuclear Factor-Erythroid 1C
Transcription Factor GATA3
Transcription Factor, GATA3



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