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Descriptor English: Hepatocyte Nuclear Factor 1-beta
Descriptor Spanish: Factor Nuclear 1-beta del Hepatocito
Descriptor factor nuclear 1-beta del hepatocito
Scope note: Factor nuclear del hepatocito que está íntimamente relacionado con el FACTOR NUCLEAR 1-ALFA DEL HEPATOCITO, aunque se expresa muy débilmente en el HÍGADO. Las mutaciones en el factor nuclear 1-beta del hepatocito se asocian con QUISTES renales y el desarrollo de DIABETES MELLITUS DE APARICIÓN TARDÍA tipo 5.
Descriptor Portuguese: Fator 1-beta Nuclear de Hepatócito
Descriptor French: Facteur nucléaire hépatocytaire HNF-1 bêta
Entry term(s): HNF 1beta
HNF-1beta
Hepatocyte Nuclear Factor 1 beta
Hepatocyte Nuclear Factor 1beta
Hepatocyte Nuclear Factor-1beta
Liver Specific Transcription Factor LF B3
Liver Specific Transcription Factor LF-B3
Variant Hepatic Nuclear Factor 1
Tree number(s): D12.776.260.262.500.750
D12.776.260.400.218.750
D12.776.660.352.500.750
D12.776.930.318.500.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051539
Scope note: A hepatocyte nuclear factor that is closely related to HEPATOCYTE NUCLEAR FACTOR 1-ALPHA but is only weakly expressed in the LIVER. Mutations in hepatocyte nuclear factor 1-beta are associated with renal CYSTS and MATURITY-ONSET DIABETES MELLITUS type 5.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 138674-15-4
Public MeSH Note: 2006; HEPATOCYTE NUCLEAR FACTOR 1-BETA was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1991-2005
History Note: 2006(1991)
DeCS ID: 50998
Unique ID: D051539
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/07/06
Revision Date: 2017/06/30
Hepatocyte Nuclear Factor 1-beta - Preferred
Concept UI M0187934
Scope note A hepatocyte nuclear factor that is closely related to HEPATOCYTE NUCLEAR FACTOR 1-ALPHA but is only weakly expressed in the LIVER. Mutations in hepatocyte nuclear factor 1-beta are associated with renal CYSTS and MATURITY-ONSET DIABETES MELLITUS type 5.
Preferred term Hepatocyte Nuclear Factor 1-beta
Entry term(s) HNF 1beta
HNF-1beta
Hepatocyte Nuclear Factor 1 beta
Hepatocyte Nuclear Factor 1beta
Hepatocyte Nuclear Factor-1beta
Liver Specific Transcription Factor LF B3
Liver Specific Transcription Factor LF-B3
Variant Hepatic Nuclear Factor 1



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