Search
Descriptor English: Hepatocyte Nuclear Factor 1
Descriptor Spanish: Factor Nuclear 1 del Hepatocito
Descriptor factor nuclear 1 del hepatocito
Scope note: Factor de transcripción y homeodominio proteico que regula la expresión de numerosas proteínas hepáticas, incluidas la SEROALBÚMINA, el fibrinógeno beta y la ALFA-1 ANTITRIPSINA. Está compuesto por heterodímeros u homodímeros del FACTOR NUCLEAR 1-ALFA DEL HEPATOCITO y el FACTOR NUCLEAR 1-BETA DEL HEPATOCITO.
Descriptor Portuguese: Fator 1 Nuclear de Hepatócito
Descriptor French: Facteur nucléaire hépatocytaire HNF-1
Entry term(s): HNF 1 Protein
HNF-1 Protein
HNF1 Transcription Factor
Hepatic Nuclear Factor 1
Transcription Factor, HNF1
Tree number(s): D12.776.260.262.500
D12.776.260.400.218
D12.776.660.352.500
D12.776.930.318.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051537
Scope note: A transcription factor and homeodomain protein that regulates the expression of a large set of hepatic proteins including SERUM ALBUMIN; beta-fibrinogen; and ALPHA 1-ANTITRYPSIN. It is composed of hetero- or homo-dimers of HEPATOCYTE NUCLEAR FACTOR 1-ALPHA and HEPATOCYTE NUCLEAR FACTOR 1-BETA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 126548-29-6
Public MeSH Note: 2006; HEPATOCYTE NUCLEAR FACTOR 1 was indexed under DNA-BINDING PROTEINS & NUCLEAR PROTEINS & TRANSCRIPTION FACTORS 1989-2005
History Note: 2006(1989)
DeCS ID: 50996
Unique ID: D051537
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/07/06
Revision Date: 2017/06/30
Hepatocyte Nuclear Factor 1 - Preferred
Concept UI M0170063
Scope note A transcription factor and homeodomain protein that regulates the expression of a large set of hepatic proteins including SERUM ALBUMIN; beta-fibrinogen; and ALPHA 1-ANTITRYPSIN. It is composed of hetero- or homo-dimers of HEPATOCYTE NUCLEAR FACTOR 1-ALPHA and HEPATOCYTE NUCLEAR FACTOR 1-BETA.
Preferred term Hepatocyte Nuclear Factor 1
Entry term(s) HNF 1 Protein
HNF-1 Protein
HNF1 Transcription Factor
Hepatic Nuclear Factor 1
Transcription Factor, HNF1



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey