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Descriptor English: PAX5 Transcription Factor
Descriptor Spanish: Factor de Transcripción PAX5
Descriptor factor de transcripción PAX5
Entry term(s) proteína activadora específica de los linfocitos B
proteína paired box 5
Scope note: Factor de transcripción "paired box" (PAX) esencial para la DIFERENCIACIÓN CELULAR de los LINFOCITOS B. Funciona tanto como activador de la transcripción como represor para mediar el compromiso de los linfocitos B.
Descriptor Portuguese: Fator de Transcrição PAX5
Descriptor French: Protéine activatrice spécifique des lymphocytes B
Entry term(s): B Cell Specific Activator Protein
B Cell Specific Transcription Factor
B Cell-Specific Transcription Factor
B-Cell-Specific Activator Protein
Early B Cell Specific Binding Protein 1
Early B Cell-Specific Binding Protein-1
PAX5, Transcription Factor
Paired Box 5 Protein
Pax5A Transcription Factor
Transcription Factor PAX5
Transcription Factor, PAX5
Transcription Factor, Pax5A
Tree number(s): D12.776.260.645.500
D12.776.930.700.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051757
Scope note: A paired box transcription factor that is essential for CELL DIFFERENTIATION of B-LYMPHOCYTES. It functions both as a transcriptional activator and repressor to mediate B-cell commitment.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; B-CELL-SPECIFIC ACTIVATOR PROTEIN was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 2002-2005, & under NUCLEAR PROTEINS 1992-2001
History Note: 2006(1992)
DeCS ID: 51031
Unique ID: D051757
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/05/27
PAX5 Transcription Factor - Preferred
Concept UI M0200645
Scope note A paired box transcription factor that is essential for CELL DIFFERENTIATION of B-LYMPHOCYTES. It functions both as a transcriptional activator and repressor to mediate B-cell commitment.
Preferred term PAX5 Transcription Factor
Entry term(s) B Cell Specific Activator Protein
B Cell Specific Transcription Factor
B Cell-Specific Transcription Factor
B-Cell-Specific Activator Protein
Early B Cell Specific Binding Protein 1
Early B Cell-Specific Binding Protein-1
PAX5, Transcription Factor
Paired Box 5 Protein
Transcription Factor PAX5
Transcription Factor, PAX5
Pax5A Transcription Factor - Narrower
Concept UI M0394835
Scope note Pax5A transcription factor is the major isoform of B-cell-specific activator protein.
Preferred term Pax5A Transcription Factor
Entry term(s) Transcription Factor, Pax5A



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