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Descriptor English: PAX8 Transcription Factor
Descriptor Spanish: Factor de Transcripción PAX8
Descriptor factor de transcripción PAX8
Entry term(s) proteína paired box PAX8
Scope note: Factor de transcripción con una pareja de dominios (paired box, PAX) implicado en el desarrollo de los TIROCITOS y el control de la expresión génica específica de la tiroides. Las mutaciones en el gen PAX8 se asocian a la DISGENESIA TIROIDEA y a las NEOPLASIAS DE LA TIROIDES.
Descriptor Portuguese: Fator de Transcrição PAX8
Descriptor French: Facteur de transcription PAX-8
Entry term(s): PAX8 Paired-Box Protein
Paired Box Protein, PAX8
Paired-Box Protein, PAX8
Transcription Factor, PAX8
Tree number(s): D12.776.260.645.906
D12.776.930.700.906
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072636
Scope note: A paired box transcription factor that functions in the development of THYROCYTES and the control of thyroid-specific gene expression. Mutations in the PAX8 gene are associated with THYROID DYSGENESIS and THYROID NEOPLASMS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA-Binding Proteins (1993-2016)
Nuclear Proteins (1993-2016)
Paired Box Transcription Factors (2006-2016)
Trans-Activators (1993-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56608
Unique ID: D000072636
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/07/01
PAX8 Transcription Factor - Preferred
Concept UI M000617670
Scope note A paired box transcription factor that functions in the development of THYROCYTES and the control of thyroid-specific gene expression. Mutations in the PAX8 gene are associated with THYROID DYSGENESIS and THYROID NEOPLASMS.
Preferred term PAX8 Transcription Factor
Entry term(s) PAX8 Paired-Box Protein
Paired Box Protein, PAX8
Paired-Box Protein, PAX8
Transcription Factor, PAX8



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