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Descriptor English: Glial Cell Line-Derived Neurotrophic Factors
Descriptor Spanish: Factores Neurotróficos Derivados de la Línea Celular Glial
Descriptor factores neurotróficos derivados de células gliales
Entry term(s) factores neurotróficos derivados de la línea celular glial
Scope note: Familia de factores de crecimiento neural, íntimamente relacionados, que favorecen la supervivencia de la NEURONA. Se unen a los RECEPTORES GDNF y estimulan la TRANSDUCCIÓN DE SEÑALES a través de la PROTEÍNA PROTOONCOGÉNICA C-RET.
Descriptor Portuguese: Fatores Neurotróficos Derivados de Linhagem de Célula Glial
Descriptor French: Facteurs neurotrophiques dérivés des cellules gliales
Entry term(s): GDNF Family Ligands
GDNF Protein Family
Glial Cell Line Derived Neurotrophic Factors
Tree number(s): D12.644.276.860.381
D12.776.467.860.381
D12.776.631.600.381
D23.529.850.381
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051098
Scope note: A family of closely related nerve growth factors that promote NEURON survival. They bind to GDNF RECEPTORS and stimulate SIGNAL TRANSDUCTION through PROTO-ONCOGENE PROTEIN C-RET.
Annotation: GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR is also available
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006
History Note: 2006
DeCS ID: 51101
Unique ID: D051098
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23
Glial Cell Line-Derived Neurotrophic Factors - Preferred
Concept UI M0479211
Scope note A family of closely related nerve growth factors that promote NEURON survival. They bind to GDNF RECEPTORS and stimulate SIGNAL TRANSDUCTION through PROTO-ONCOGENE PROTEIN C-RET.
Preferred term Glial Cell Line-Derived Neurotrophic Factors
Entry term(s) GDNF Family Ligands
GDNF Protein Family
Glial Cell Line Derived Neurotrophic Factors



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