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Descriptor English: Toll-Like Receptors
Descriptor Spanish: Receptores Toll-Like
Descriptor receptores similares a toll
Entry term(s) RTL
receptores semejantes a toll
Scope note: Familia de receptores de reconocimiento de patrones caracterizados por poseer un dominio extracelular rico en leucina y un dominio citoplásmico que comparte homología con el RECEPTOR DE INTERLEUCINA 1 y la proteína toll de DROSOPHILA. Tras la identificación del patógeno, los receptores toll-like reclutan y activan una serie de PROTEÍNAS ADAPTADORAS DE TRANSDUCCIÓN DE SEÑALES.
Descriptor Portuguese: Receptores Toll-Like
Descriptor French: Récepteurs de type Toll
Entry term(s): Receptor, Toll-Like
Receptors, Toll Like
Receptors, Toll-Like
Toll Like Receptor
Toll Like Receptors
Toll-Like Receptor
Tree number(s): D12.776.543.750.705.910.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051193
Scope note: A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
Annotation: general; prefer specifics
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Public MeSH Note: 2006; TOLL-LIKE RECEPTOR was indexed under MEMBRANE GLYCOPROTEINS & RECEPTORS, CELL SURFACE 1998-2005
History Note: 2006(1998)
DeCS ID: 51130
Unique ID: D051193
NLM Classification: QW 570
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Toll-Like Receptors - Preferred
Concept UI M0286281
Scope note A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
Preferred term Toll-Like Receptors
Entry term(s) Receptor, Toll-Like
Receptors, Toll Like
Receptors, Toll-Like
Toll Like Receptor
Toll Like Receptors
Toll-Like Receptor



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