| Descriptor English: | Keratin-4 | ||||||
| Descriptor Spanish: | 
                                Queratina-4                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Queratina-4 | ||||||
| Descriptor French: | Kératine-4 | ||||||
| Entry term(s): | 
                                    Cytokeratin 4 Cytokeratin-4 Keratin 4  | 
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| Tree number(s): | 
                                        D05.750.078.593.450.600.400 D12.776.220.475.450.600.400 D12.776.860.607.650.400  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D053527 | ||||||
| Scope note: | A type II keratin that is found associated with the KERATIN-13 in the internal stratified EPITHELIUM. Defects in gene for keratin-4 are a cause of HEREDITARY MUCOSAL LEUKOKERATOSIS. | 
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| Allowable Qualifiers: | 
                                                                        AD                                                            administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine  | 
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| Entry Combination: | 
                                                                            deficiency:Leukokeratosis, Hereditary Mucosal
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| Previous Indexing: | 
                                                Keratins (1989-2006) | 
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| Public MeSH Note: | 2007; for CYTOKERATIN-4 see KERATIN 1989-2006 | 
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| History Note: | 2007(1989) | 
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| DeCS ID: | 52197 | ||||||
| Unique ID: | D053527 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2007/01/01 | ||||||
| Date of Entry: | 2006/07/05 | 
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                                        CHEMICALS AND DRUGS
 
Macromolecular Substances [D05]Macromolecular Substances - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins 
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                        Keratin-4                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0011949 | 
                                
| Scope note | A type II keratin that is found associated with the KERATIN-13 in the internal stratified EPITHELIUM. Defects in gene for keratin-4 are a cause of HEREDITARY MUCOSAL LEUKOKERATOSIS. | 
| Preferred term | Keratin-4 | 
| Entry term(s) | 
                                        
                                                                                            Cytokeratin 4                                                 Cytokeratin-4 Keratin 4  | 
                                
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