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Descriptor English: Keratin-2
Descriptor Spanish: Queratina-2
Descriptor queratina-2
Entry term(s) queratina 2
Scope note: Queratina de tipo II que se expresa en la parte superior del estrato espinoso de los QUERATINOCITOS epidérmicos. Las mutaciones de los genes que codifican la queratina 2A se han asociado a ICTIOSIS AMPOLLOSA DE SIEMENS.
Descriptor Portuguese: Queratina-2
Descriptor French: Kératine-2
Entry term(s): Cytokeratin 2
Cytokeratin-2
Keratin 2
Keratin 2A
Keratin 2B
Keratin 2E
Keratin-2A
Keratin-2B
Keratin-2E
Keratin-2P
Tree number(s): D05.750.078.593.450.600.200
D12.776.220.475.450.600.200
D12.776.860.607.650.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053557
Scope note: A type II keratin found expressed in the upper spinous layer of epidermal KERATINOCYTES. Mutations in genes that encode keratin-2A have been associated with ICHTHYOSIS BULLOSA OF SIEMENS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Keratins (1994-2006)
Public MeSH Note: 2007
History Note: 2007
DeCS ID: 52195
Unique ID: D053557
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Keratin-2 - Preferred
Concept UI M0494572
Scope note A type II keratin found expressed in the upper spinous layer of epidermal KERATINOCYTES. Mutations in genes that encode keratin-2A have been associated with ICHTHYOSIS BULLOSA OF SIEMENS.
Preferred term Keratin-2
Entry term(s) Cytokeratin 2
Cytokeratin-2
Keratin 2
Keratin-2B - Narrower
Concept UI M0494621
Preferred term Keratin-2B
Entry term(s) Keratin 2B
Keratin-2P
Keratin-2A - Narrower
Concept UI M0494620
Preferred term Keratin-2A
Entry term(s) Keratin 2A
Keratin 2E
Keratin-2E



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