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Descriptor English: Keratin-1
Descriptor Spanish: Queratina-1
Descriptor queratina 1
Entry term(s) queratina-1
Scope note: Queratina de tipo II que se encuentra asociada con la QUERATINA 10 en células epidérmicas bien diferenciadas, como las del estrato córneo. Las mutaciones de los genes que codifican la queratina 1 se han asociado a la HIPERQUERATOSIS EPIDERMOLÍTICA.
Descriptor Portuguese: Queratina-1
Descriptor French: Kératine-1
Entry term(s): Keratin 1
Tree number(s): D05.750.078.593.450.600.100
D12.776.220.475.450.600.100
D12.776.860.607.650.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053556
Scope note: A type II keratin that is found associated with the KERATIN-10 in terminally differentiated epidermal cells such as those that form the stratum corneum. Mutations in the genes that encode keratin-1 have been associated with HYPERKERATOSIS, EPIDERMOLYTIC.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Hyperkeratosis, Epidermolytic
Previous Indexing: Keratin (1964-2006)
Public MeSH Note: 2007
History Note: 2007
DeCS ID: 52194
Unique ID: D053556
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Keratin-1 - Preferred
Concept UI M0494571
Scope note A type II keratin that is found associated with the KERATIN-10 in terminally differentiated epidermal cells such as those that form the stratum corneum. Mutations in the genes that encode keratin-1 have been associated with HYPERKERATOSIS, EPIDERMOLYTIC.
Preferred term Keratin-1
Entry term(s) Keratin 1



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