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Descriptor English: Apolipoprotein C-II
Descriptor Spanish: Apolipoproteína C-II
Descriptor apolipoproteína C-II
Scope note: Proteína de 9 kDa componente de las LIPOPROTEÍNAS DE MUY BAJA DENSIDAD. Contiene un cofactor para la LIPOPROTEÍNA LIPASA y activa varias triacilglicerol lipasas. La asociación de Apo C-II con los QUILOMICRONES del plasma, VLDL y LIPOPROTEÍNAS DE ALTA DENSIDAD es reversible y cambia rápidamente en función del metabolismo de los triglicéridos. Clínicamente, la deficiencia en Apo C-II es similar a la deficiencia en lipoproteína lipasa (HIPERLIPOPROTEINEMIA DE TIPO I) y se la denomina, por consiguiente, hiperlipoproteinemia de tipo IB.
Descriptor Portuguese: Apolipoproteína C-II
Descriptor French: Apolipoprotéine C-II
Entry term(s): Apo C II
Apo C-II
ApoC2
Apolipoprotein C 2
Apolipoprotein C II
Apolipoprotein C-2
Apolipoprotein CII
Apoprotein C II
Apoprotein C-II
Tree number(s): D10.532.091.400.750
D12.776.070.400.400.750
D12.776.521.120.400.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053304
Scope note: A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Apolipoproteins C (1977-2006)
Public MeSH Note: 2007; APOLIPOPROTEIN C-II was indexed under APOLIPOPROTEINS C 1984-2006 & under APOLIPOPROTEINS 1978-1984
History Note: 2007; use APOLIPOPROTEIN C-II (NM) 1978-2006
Related: Hyperlipoproteinemia Type I MeSH
DeCS ID: 52263
Unique ID: D053304
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2009/07/06
Apolipoprotein C-II - Preferred
Concept UI M0066119
Scope note A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.
Preferred term Apolipoprotein C-II
Entry term(s) Apo C II
Apo C-II
ApoC2
Apolipoprotein C 2
Apolipoprotein C II
Apolipoprotein C-2
Apolipoprotein CII
Apoprotein C II
Apoprotein C-II



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