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Descriptor English: Apolipoprotein C-III
Descriptor Spanish: Apolipoproteína C-III
Descriptor apolipoproteína C-III
Scope note: Proteína de 9 kDa componente de las LIPOPROTEÍNAS DE MUY BAJA DENSIDAD y de los QUILOMICRONES REMANENTES. La Apo C-III, sintetizada en el hígado, es inhibidor de la LIPOPROTEÍNA LIPASA. La Apo C-III modula la unión de los restos de quilomicrones y de las VLDL a los receptores (RECEPTORES DE LDL) disminuyendo así la captación de partículas ricas en triglicéridos por los hepatocitos y la posterior degradación. La Apo C-III normal está glicosilada. Hay varias formas polimórficas con cantidades variables de ÁCIDO SIÁLICO (Apo C-III-O, Apo C-III-1 y Apo C-III-2).
Descriptor Portuguese: Apolipoproteína C-III
Descriptor French: Apolipoprotéine C-III
Entry term(s): Apo C III
Apo C III 2
Apo C-III
Apo C-III, Sialyl
Apo C-III-2
ApoC III
ApoC-III
Apolipoprotein C III
Apolipoprotein C III 0
Apolipoprotein C III 1
Apolipoprotein C-III, Sialyl
Apolipoprotein C-III-0
Apolipoprotein C-III-1
Apolipoprotein CIII
Sialyl Apo C III
Sialyl Apo C-III
Sialyl Apolipoprotein C III
Sialyl Apolipoprotein C-III
Tree number(s): D10.532.091.400.875
D12.776.070.400.400.875
D12.776.521.120.400.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053305
Scope note: A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Apolipoproteins C (1977-2006)
Public MeSH Note: 2007; APOLIPOPROTEIN C-III was indexed under APOLIPOPROTEINS C 1985-2006 & under APOLIPOPROTEINS 1979-1984
History Note: 2007; use APOLIPOPROTEIN C-III (NM) 1979-2006
DeCS ID: 52264
Unique ID: D053305
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2013/07/09
Apolipoprotein C-III - Preferred
Concept UI M0073736
Scope note A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).
Preferred term Apolipoprotein C-III
Entry term(s) Apo C III
Apo C-III
Apolipoprotein C III
Apolipoprotein CIII
Apolipoprotein C-III-1 - Narrower
Concept UI M0073732
Preferred term Apolipoprotein C-III-1
Entry term(s) Apolipoprotein C III 1
ApoC-III - Narrower
Concept UI M0489164
Preferred term ApoC-III
Entry term(s) ApoC III
Apolipoprotein C-III-0 - Narrower
Concept UI M0073731
Preferred term Apolipoprotein C-III-0
Entry term(s) Apolipoprotein C III 0
Sialyl Apo C-III - Narrower
Concept UI M0073734
Preferred term Sialyl Apo C-III
Entry term(s) Apo C-III, Sialyl
Apolipoprotein C-III, Sialyl
Sialyl Apo C III
Sialyl Apolipoprotein C III
Sialyl Apolipoprotein C-III
Apo C-III-2 - Narrower
Concept UI M0073729
Preferred term Apo C-III-2
Entry term(s) Apo C III 2



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