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Descriptor English: Chromogranin A
Descriptor Spanish: Cromogranina A
Descriptor cromogranina A
Entry term(s) proteína CHGA
Scope note: Tipo de cromogranina que se aisló por vez primera a partir de las CÉLULAS CROMAFINES de la MÉDULA SUPRARRENAL, pero que también se encuentra en otros tejidos y en muchas especies, incluidas la especie humana, la bobina, la rata, el ratón y otras. Se trata de una proteína ácida con 431-445 aminoácidos. Contiene fragmentos que inhiben la vasoconstricción o liberación de hormonas y neurotransmisores, mientras que otros fragmentos ejercen acciones antimicrobianas.
Descriptor Portuguese: Cromogranina A
Descriptor French: Chromogranine A
Entry term(s): CHGA Protein
Parathyroid Secretory Protein
Secretory Protein I, Parathyroid Gland
Secretory Protein, Parathyroid
Tree number(s): D12.776.631.199.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053379
Scope note: A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is also found in other tissues and in many species including human, bovine, rat, mouse, and others. It is an acidic protein with 431 to 445 amino acid residues. It contains fragments that inhibit vasoconstriction or release of hormones and neurotransmitter, while other fragments exert antimicrobial actions.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Adrenal Medulla (1968-2003)
Chromogranins (1973-2006)
Public MeSH Note: 2007; CHROMOGRANIN A was indexed under CHROMOGRANINS 1981-2006
History Note: 2007 (1981)
DeCS ID: 52400
Unique ID: D053379
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/05/27
Chromogranin A - Preferred
Concept UI M0492852
Scope note A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is also found in other tissues and in many species including human, bovine, rat, mouse, and others. It is an acidic protein with 431 to 445 amino acid residues. It contains fragments that inhibit vasoconstriction or release of hormones and neurotransmitter, while other fragments exert antimicrobial actions.
Preferred term Chromogranin A
Entry term(s) CHGA Protein
Parathyroid Secretory Protein
Secretory Protein I, Parathyroid Gland
Secretory Protein, Parathyroid



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