Search
Descriptor English: Alpha-Amanitin
Descriptor Spanish: Alfa-Amanitina
Descriptor alfa-amanitina
Entry term(s) amanitina alfa
Scope note: Octapéptido cíclico con un puente tioéter entre la cistina y el triptófano. Inhibe la ARN POLIMERASA II. La intoxicación por este compuesto puede requerir un TRASPLANTE HEPÁTICO.
Descriptor Portuguese: Alfa-Amanitina
Descriptor French: alpha-Amanitine
Entry term(s): Alpha Amanitin
Alpha Amanitine
Alpha-Amanitine
Tree number(s): D04.345.566.050.111
D12.644.456.050.111
D12.644.641.050.111
D23.946.587.175.111
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053959
Scope note: A cyclic octapeptide with a thioether bridge between the cystine and tryptophan. It inhibits RNA POLYMERASE II. Poisoning may require LIVER TRANSPLANTATION.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Poisons
Nucleic Acid Synthesis Inhibitors
Previous Indexing: Amanitins (1980-2007)
Public MeSH Note: 2008; see AMANITINS 1980-2007
History Note: 2008; use AMANITINS 1980-2007
Related: Mushroom Poisoning MeSH
DeCS ID: 52652
Unique ID: D053959
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2018/06/29
Alpha-Amanitin - Preferred
Concept UI M0000844
Scope note A cyclic octapeptide with a thioether bridge between the cystine and tryptophan. It inhibits RNA POLYMERASE II. Poisoning may require LIVER TRANSPLANTATION.
Preferred term Alpha-Amanitin
Entry term(s) Alpha Amanitin
Alpha Amanitine
Alpha-Amanitine



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey