| Descriptor English: | Chemokine CXCL12 | ||||||
| Descriptor Spanish: |
Quimiocina CXCL12
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| Descriptor Portuguese: | Quimiocina CXCL12 | ||||||
| Descriptor French: | Chimiokine CXCL12 | ||||||
| Entry term(s): |
CXCL12 Chemokine CXCL12, Chemokine Cell-Derived Factor-1beta, Stromal Chemokine (C-X-C Motif) Ligand 12 Chemokine, CXCL12 Growth-Stimulating Factor, Pre-B-Cell Pre B Cell Growth Stimulating Factor Pre-B-Cell Growth-Stimulating Factor SDF 1alpha SDF 1beta SDF-1alpha SDF-1beta SDF1 3'A SDF1-3'A Stromal Cell Derived Factor 1 Stromal Cell Derived Factor 1alpha Stromal Cell Derived Factor 1beta Stromal Cell-Derived Factor 1 Stromal Cell-Derived Factor-1alpha Stromal Cell-Derived Factor-1beta |
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| Tree number(s): |
D12.644.276.374.200.120.600 D12.776.467.374.200.120.600 D23.125.300.120.600 D23.469.200.120.600 D23.529.374.200.120.600 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D054377 | ||||||
| Scope note: | A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2008; CXCL12 CHEMOKINE (now CHEMOKINE CXCL12) was indexed under CHEMOKINES, CXC 1993-2007; STROMAL CELL-DERIVED FACTOR-1BETA was indexed under CYTOKINES 2001-2007 |
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| History Note: | 2008(1993) |
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| DeCS ID: | 52780 | ||||||
| Unique ID: | D054377 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2008/01/01 | ||||||
| Date of Entry: | 2007/07/09 | ||||||
| Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Chemokine CXCL12
- Preferred
Stromal Cell-Derived Factor-1alpha
- Narrower
Stromal Cell-Derived Factor-1beta
- Narrower
SDF1-3'A
- Narrower
| Concept UI |
M0219484 |
| Scope note | A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing. |
| Preferred term | Chemokine CXCL12 |
| Entry term(s) |
CXCL12 Chemokine CXCL12, Chemokine Chemokine (C-X-C Motif) Ligand 12 Chemokine, CXCL12 Growth-Stimulating Factor, Pre-B-Cell Pre B Cell Growth Stimulating Factor Pre-B-Cell Growth-Stimulating Factor Stromal Cell Derived Factor 1 Stromal Cell-Derived Factor 1 |
| Concept UI |
M0504483 |
| Preferred term | Stromal Cell-Derived Factor-1alpha |
| Entry term(s) |
SDF 1alpha SDF-1alpha Stromal Cell Derived Factor 1alpha |
| Concept UI |
M0219486 |
| Preferred term | Stromal Cell-Derived Factor-1beta |
| Entry term(s) |
Cell-Derived Factor-1beta, Stromal SDF 1beta SDF-1beta Stromal Cell Derived Factor 1beta |
| Concept UI |
M0229029 |
| Scope note | Polymorphic allele of CXCL12. |
| Preferred term | SDF1-3'A |
| Entry term(s) |
SDF1 3'A |
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