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Descriptor in English: Platelet Factor 4
Descriptor in Spanish: Factor Plaquetario 4
Descriptor in Portuguese: Fator Plaquetário 4
Descriptor in French: Facteur-4 plaquettaire
Entry term(s): Antiheparin Factor
CXCL4 Chemokine
CXCL4, Chemokine
Chemokine CXCL4
Chemokine, CXCL4
Heparin Neutralizing Protein
PF4 (Platelet Factor 4)
gamma Thromboglobulin
gamma-Thromboglobulin
Tree number(s): D12.644.276.374.200.120.900
D12.776.124.125.720
D12.776.467.374.200.120.900
D23.119.940
D23.125.300.120.900
D23.469.200.120.900
D23.529.374.200.120.900
Scope note: A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 84(76); was see under BLOOD COAGULATION FACTORS 1976-83
DeCS UI: 22259
Descriptor UI: D010978
Date Established: 1984/01/01
Date of Entry: 1975/07/25
Revision Date: 2007/07/09
Platelet Factor 4 - Preferred
Concept UI M0017019
Scope note A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.
Preferred term Platelet Factor 4
Entry term(s) Antiheparin Factor
CXCL4 Chemokine
CXCL4, Chemokine
Chemokine CXCL4
Chemokine, CXCL4
Heparin Neutralizing Protein
PF4 (Platelet Factor 4)
gamma Thromboglobulin
gamma-Thromboglobulin



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