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Descriptor English: Receptors, Leptin
Descriptor Spanish: Receptores de Leptina
Descriptor receptores de leptina
Entry term(s) antígenos CD295
receptor OB
receptor de leptina
Scope note: Receptores de superficie celular para el factor de obesidad (LEPTINA), una hormona secretada por los ADIPOCITOS BLANCOS. Respecto de la interacción del receptor de leptina, la señal es mediada por vía JAK2/STAT3 para regular el ingreso de alimentos, el balance energético y el almacenamiento de grasas.
Descriptor Portuguese: Receptores para Leptina
Descriptor French: Récepteurs à la leptine
Entry term(s): Antigens, CD295
CD295 Antigens
LEPR Protein
Leptin Binding Protein
Leptin Receptor
Leptin Receptor, Large Isoform
Leptin Receptor, Small Isoform
Leptin Receptors
Leptin-Binding Protein
OB Receptor
OBRa Receptor
OBRb Receptor
Receptor, Leptin
Receptor, OB
Receptor, OBRa
Receptor, OBRb
Tree number(s): D12.776.543.750.650.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054411
Scope note: Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Receptors, Cell Surface (1995-2007)
Public MeSH Note: 2008; LEPTIN RECEPTOR was indexed under RECEPTORS, CELL SURFACE 1996-2007
History Note: 2008 (1996)
Entry Version: RECEPT LEPTIN
DeCS ID: 52801
Unique ID: D054411
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2016/06/17
Receptors, Leptin - Preferred
Concept UI M0256281
Scope note Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
Preferred term Receptors, Leptin
Entry term(s) Antigens, CD295
CD295 Antigens
LEPR Protein
Leptin Binding Protein
Leptin Receptor
Leptin Receptors
Leptin-Binding Protein
OB Receptor
Receptor, Leptin
Receptor, OB
OBRa Receptor - Narrower
Concept UI M0504721
Scope note Isoform A is expressed in fetal liver, hematopoietic tissues, and choroid plexus.
Preferred term OBRa Receptor
Entry term(s) Receptor, OBRa
OBRb Receptor - Narrower
Concept UI M0256275
Scope note Isoform B is highly expressed in hypothalamus.
Preferred term OBRb Receptor
Entry term(s) Leptin Receptor, Large Isoform
Receptor, OBRb
Leptin Receptor, Small Isoform - Narrower
Concept UI M0256274
Preferred term Leptin Receptor, Small Isoform



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