| Descriptor English: | Receptors, KIR | ||||||
| Descriptor Spanish: |
Receptores KIR
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| Descriptor Portuguese: | Receptores KIR | ||||||
| Descriptor French: | Récepteurs KIR | ||||||
| Entry term(s): |
Family Receptors, KIR Immunoglobulin-Like Receptor, Killer Inhibitory Receptor, Killer Inhibitory Receptors, Killer KIR Family Receptors KIR Receptor KIR Receptors Killer Cell Immunoglobulin Like Receptor Killer Cell Immunoglobulin Like Receptors Killer Cell Immunoglobulin-Like Receptor Killer Cell Immunoglobulin-Like Receptors Killer Immunoglobulin Like Receptor Killer Immunoglobulin-Like Receptor Killer Immunoglobulin-Like Receptor (KIR) Family of Receptors Killer Inhibitory Receptor Killer Inhibitory Receptors Receptor, KIR Receptor, Killer Immunoglobulin-Like Receptor, Killer Inhibitory Receptor, p58 NK Cell Receptors, KIR Family Receptors, Killer Inhibitory p58 NK Cell Inhibitory Receptor p58 NK Cell Receptor p58 NK Cell Receptors p58 Natural Killer Cell Receptor |
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| Tree number(s): |
D12.776.543.750.705.895.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D054340 | ||||||
| Scope note: | A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells. |
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| Annotation: | general; prefer specifics |
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| Allowable Qualifiers: |
AD administration & dosage AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CH chemistry CL classification DE drug effects DF deficiency GE genetics HI history IM immunology IP isolation & purification ME metabolism PH physiology RE radiation effects TU therapeutic use UL ultrastructure |
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| Public MeSH Note: | 2008; KIR RECEPTORS (now RECEPTORS, KIR) was indexed under RECEPTORS, IMMUNOLOGIC 1997-2007 |
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| History Note: | 2008(1997) |
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| DeCS ID: | 52815 | ||||||
| Unique ID: | D054340 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2008/01/01 | ||||||
| Date of Entry: | 2007/07/09 | ||||||
| Revision Date: | 2008/07/08 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Receptors, KIR
- Preferred
| Concept UI |
M0281250 |
| Scope note | A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells. |
| Preferred term | Receptors, KIR |
| Entry term(s) |
Family Receptors, KIR Immunoglobulin-Like Receptor, Killer Inhibitory Receptor, Killer Inhibitory Receptors, Killer KIR Family Receptors KIR Receptor KIR Receptors Killer Cell Immunoglobulin Like Receptor Killer Cell Immunoglobulin Like Receptors Killer Cell Immunoglobulin-Like Receptor Killer Cell Immunoglobulin-Like Receptors Killer Immunoglobulin Like Receptor Killer Immunoglobulin-Like Receptor Killer Immunoglobulin-Like Receptor (KIR) Family of Receptors Killer Inhibitory Receptor Killer Inhibitory Receptors Receptor, KIR Receptor, Killer Immunoglobulin-Like Receptor, Killer Inhibitory Receptor, p58 NK Cell Receptors, KIR Family Receptors, Killer Inhibitory p58 NK Cell Inhibitory Receptor p58 NK Cell Receptor p58 NK Cell Receptors p58 Natural Killer Cell Receptor |
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