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Descriptor English: Iridocorneal Endothelial Syndrome
Descriptor Spanish: Síndrome Endotelial Iridocorneal
Descriptor síndrome endotelial iridocorneal
Entry term(s) síndrome EIC
Scope note: Agrupación de tres afecciones estrechamente vinculadas: iris nevus o Síndrome de Cogan-Reese, Síndrome de Chandler y atrofia del iris esencial (progresiva). Las características más comunes de este síndrome son el movimiento de las células endoteliales fuera de la córnea hacia el iris que provoca inflamación corneal, distorsión del iris y grados variables de distorsión de la pupila. Los movimientos anormales de las células obstruyen los canales de flujo de salida de los líquidos del ojo causando GLAUCOMA. 
Descriptor Portuguese: Síndrome Endotelial Iridocorneana
Descriptor French: Syndrome irido-cornéo-endothélial
Entry term(s): Chandler Syndrome
Chandler's Syndrome
Chandlers Syndrome
Endothelial Syndrome, Iridocorneal
Endothelial Syndromes, Iridocorneal
ICE Syndrome
Iridocorneal Endothelial Syndromes
Iris Atrophy with Corneal Edema and Glaucoma
Tree number(s): C11.204.497
C11.941.375.322
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D057129
Scope note: A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Corneal Diseases (1979-2009)
Iris Diseases (1979-2009)
Public MeSH Note: 2010
History Note: 2010
Related: Glaucoma MeSH
DeCS ID: 53526
Unique ID: D057129
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2020/02/28
Iridocorneal Endothelial Syndrome - Preferred
Concept UI M0534719
Scope note A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.
Preferred term Iridocorneal Endothelial Syndrome
Entry term(s) Endothelial Syndrome, Iridocorneal
Endothelial Syndromes, Iridocorneal
ICE Syndrome
Iridocorneal Endothelial Syndromes
Chandler Syndrome - Narrower
Concept UI M0535646
Preferred term Chandler Syndrome
Entry term(s) Chandler's Syndrome
Chandlers Syndrome
Iris Atrophy with Corneal Edema and Glaucoma



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