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Descriptor English: Calcimimetic Agents
Descriptor Spanish: Calcimiméticos
Descriptor calcimiméticos
Entry term(s) agentes calcimiméticos
calcimimético
Scope note: Pequeñas moléculas orgánicas que actúan como activadores alostéricos del receptor sensor del calcio (CaSR) en las GLÁNDULAS PARATIROIDES y otros tejidos. Disminuyen el umbral para la activación de CaSR por los iones de calcio extracelular y disminuyen la liberación de HORMONA PARATIROIDEA (PTH) de las células paratiroideas.
Descriptor Portuguese: Calcimiméticos
Descriptor French: Calcimimétiques
Entry term(s): Agents, Calcimimetic
Tree number(s): D06.347.230
D27.505.696.399.450.230
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D057966
Scope note: Small organic molecules that act as allosteric activators of the calcium sensing receptor (CaSR) in the PARATHYROID GLANDS and other tissues. They lower the threshold for CaSR activation by extracellular calcium ions and diminish PARATHYROID HORMONE (PTH) release from parathyroid cells.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Hyperparathyroidism (1998-2010)
Public MeSH Note: 2011
History Note: 2011
DeCS ID: 54038
Unique ID: D057966
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Calcimimetic Agents - Preferred
Concept UI M0540241
Scope note Small organic molecules that act as allosteric activators of the calcium sensing receptor (CaSR) in the PARATHYROID GLANDS and other tissues. They lower the threshold for CaSR activation by extracellular calcium ions and diminish PARATHYROID HORMONE (PTH) release from parathyroid cells.
Preferred term Calcimimetic Agents
Entry term(s) Agents, Calcimimetic



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