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Descriptor English: Wnt Signaling Pathway
Descriptor Spanish: Vía de Señalización Wnt
Descriptor vía de señalización Wnt
Entry term(s) señalización Wnt
Scope note: Vía de señalización compleja cuyo nombre se deriva del gen de DROSOPHILA Wg, que cuando muta produce el fenotipo sin alas, y del gen de vertebrados INT, que se encuentra cerca de sitios de integración del VIRUS DEL TUMOR MAMARIO DEL RATÓN. La vía de señalización se inicia con la unión de las PROTEÍNAS WNT a la superficie de las células de los RECEPTORES WNT que interactúan con el COMPLEJO DE SEÑALIZACIÓN AXIN y una serie de segundos mensajeros que influyen en las acciones de la BETA-CATENINA.
Descriptor Portuguese: Via de Sinalização Wnt
Descriptor French: Voie de signalisation Wnt
Entry term(s): Canonical Wnt Pathway
Canonical Wnt Pathways
Pathway, Canonical Wnt
Pathway, Wnt
Pathway, Wnt Signaling
Pathways, Canonical Wnt
Pathways, Wnt
Pathways, Wnt Signaling
Signaling Pathway, Wnt
Signaling Pathways, Wnt
Signaling, Wnt
Wnt Pathway
Wnt Pathway, Canonical
Wnt Pathways
Wnt Pathways, Canonical
Wnt Signaling
Wnt Signaling Pathways
Wnt Signalings
Wnt beta Catenin Signaling Pathway
Wnt beta-Catenin Signaling Pathway
Tree number(s): G02.111.820.925
G04.835.925
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D060449
Scope note: A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, and the vertebrate INT gene. The signaling pathway is initiated by the binding of WNT PROTEINS to cell surface WNT RECEPTORS which interact with the AXIN SIGNALING COMPLEX and an array of second messengers that influence the actions of BETA CATENIN.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Wnt Proteins (2005-2011)
Public MeSH Note: 2012
History Note: 2012
DeCS ID: 54781
Unique ID: D060449
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Revision Date: 2020/01/16
Wnt Signaling Pathway - Preferred
Concept UI M0554003
Scope note A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, and the vertebrate INT gene. The signaling pathway is initiated by the binding of WNT PROTEINS to cell surface WNT RECEPTORS which interact with the AXIN SIGNALING COMPLEX and an array of second messengers that influence the actions of BETA CATENIN.
Preferred term Wnt Signaling Pathway
Entry term(s) Pathway, Wnt
Pathway, Wnt Signaling
Pathways, Wnt
Pathways, Wnt Signaling
Signaling Pathway, Wnt
Signaling Pathways, Wnt
Wnt Pathway
Wnt Pathways
Wnt Signaling Pathways
Wnt beta-Catenin Signaling Pathway - Narrower
Concept UI M0554004
Preferred term Wnt beta-Catenin Signaling Pathway
Entry term(s) Canonical Wnt Pathway
Canonical Wnt Pathways
Pathway, Canonical Wnt
Pathways, Canonical Wnt
Wnt Pathway, Canonical
Wnt Pathways, Canonical
Wnt beta Catenin Signaling Pathway
Wnt Signaling - Related but not broader or narrower
Concept UI M000677380
Preferred term Wnt Signaling
Entry term(s) Signaling, Wnt
Wnt Signalings



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