Descriptor English: | Cyclic GMP-Dependent Protein Kinase Type I | ||||
Descriptor Spanish: |
Proteína Quinasa Dependiente de GMP Cíclico Tipo I
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Descriptor Portuguese: | Proteína Quinase Dependente de GMP Cíclico Tipo I | ||||
Descriptor French: | Cyclic GMP-dependent protein kinase type I | ||||
Entry term(s): |
Cyclic GMP Dependent Protein Kinase Type I PKGI beta PKGIalpha PKGIbeta Protein Kinase G I alpha cGK-Ialpha cGMP Dependent Protein Kinase I cGMP Dependent Protein Kinase Ialpha cGMP Dependent Protein Kinase Ibeta cGMP-Dependent Protein Kinase I cGMP-Dependent Protein Kinase Ialpha cGMP-Dependent Protein Kinase Ibeta |
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Tree number(s): |
D08.811.913.696.620.682.700.150.150.500 D12.776.476.563.150.150.500 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D062965 | ||||
Scope note: | A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction. Two isoforms, PKGIalpha and PKGIbeta, of the type I protein kinase exist due to alternative splicing of its mRNA. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 2.7.11.12 | ||||
Public MeSH Note: | 2013; CGMP-DEPENDENT PROTEIN KINASE I (now CYCLIC GMP-DEPENDENT PROTEIN KINASE TYPE I) was indexed under CYCLIC GMP DEPENDENT PROTEIN KINASE TYPE I 1994-2012 |
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History Note: | 2013 |
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DeCS ID: | 54933 | ||||
Unique ID: | D062965 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 2013/01/01 | ||||
Date of Entry: | 2012/07/03 | ||||
Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Cyclic GMP-Dependent Protein Kinase Type I
- Preferred
cGMP-Dependent Protein Kinase Ialpha
- Narrower
cGMP-Dependent Protein Kinase Ibeta
- Narrower
Concept UI |
M0570503 |
Scope note | A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction. Two isoforms, PKGIalpha and PKGIbeta, of the type I protein kinase exist due to alternative splicing of its mRNA. |
Preferred term | Cyclic GMP-Dependent Protein Kinase Type I |
Entry term(s) |
Cyclic GMP Dependent Protein Kinase Type I cGMP Dependent Protein Kinase I cGMP-Dependent Protein Kinase I |
Concept UI |
M0230601 |
Preferred term | cGMP-Dependent Protein Kinase Ialpha |
Entry term(s) |
PKGIalpha Protein Kinase G I alpha cGK-Ialpha cGMP Dependent Protein Kinase Ialpha |
Concept UI |
M0570492 |
Preferred term | cGMP-Dependent Protein Kinase Ibeta |
Entry term(s) |
PKGI beta PKGIbeta cGMP Dependent Protein Kinase Ibeta |
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