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Descriptor English: Junctional Adhesion Molecule C
Descriptor Spanish: Molécula C de Adhesión de Unión
Descriptor molécula C de adhesión de uniones estrechas
Entry term(s) JAM-C
Scope note: Subtipo de moléculas de adhesión de uniones estrechas que se expresa en altas concentraciones en la PLACENTA, el CEREBRO, el RIÑÓN y las PLAQUETAS. Estas moléculas tienen diversas funciones como mediar en las interacciones entre leucocitos y plaquetas, en la regulación de la emigración transepitelial de los NEUTRÓFILOS y actuar como contrarreceptor de la INTEGRINA ALFA M.
Descriptor Portuguese: Molécula C de Adesão Juncional
Descriptor French: Molécule d'adhérence jonctionnelle C
Entry term(s): Junctional Adhesion Molecule 3
Tree number(s): D09.400.430.890.200.537.937
D12.776.395.550.200.537.937
D12.776.543.550.200.537.937
D12.776.543.940.600.900
D23.050.301.350.537.937
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D062786
Scope note: A junctional adhesion molecule subtype that is expressed at high levels in PLACENTA; BRAIN; KIDNEY; and PLATELETS. It serves a variety of functions such as mediating leukocyte-platelet interactions, regulating trans-epithelial migration of POLYMORPHONUCLEAR LEUKOCYTES, and acting as a counter receptor for ALPHAM INTEGRIN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Cell Adhesion Molecules (2002-2012)
Immunoglobulins (2002-2006)
Membrane Proteins (2002-2006)
Public MeSH Note: 2013
History Note: 2013
DeCS ID: 54966
Unique ID: D062786
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/06/17
Junctional Adhesion Molecule C - Preferred
Concept UI M0569270
Scope note A junctional adhesion molecule subtype that is expressed at high levels in PLACENTA; BRAIN; KIDNEY; and PLATELETS. It serves a variety of functions such as mediating leukocyte-platelet interactions, regulating trans-epithelial migration of POLYMORPHONUCLEAR LEUKOCYTES, and acting as a counter receptor for ALPHAM INTEGRIN.
Preferred term Junctional Adhesion Molecule C
Entry term(s) Junctional Adhesion Molecule 3



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