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Descriptor English: Calbindin 2
Descriptor Spanish: Calbindina 2
Descriptor calbindina 2
Entry term(s) calretinina
Scope note: Una calbindina que se expresa de forma diferencial en poblaciones definidas de NEURONAS en el SISTEMA NERVIOSO de vertebrados e invertebrados, modula la excitabilidad intrínseca neuronal e interviene en la POTENCIACIÓN A LARGO PLAZO. También se encuentra en el PULMÓN, TESTÍCULO, OVARIO, RIÑÓN y MAMA y se expresa en muchos tipos de tumores de estos tejidos. Con frecuencia se utiliza como marcador inmunohistoquímico de MESOTELIOMA.
Descriptor Portuguese: Calbindina 2
Descriptor French: Calbindine-2
Entry term(s): Calretinin
Tree number(s): D12.776.157.125.090.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064032
Scope note: A calbindin protein that is differentially expressed in distinct populations of NEURONS throughout the vertebrate and invertebrate NERVOUS SYSTEM, and modulates intrinsic neuronal excitability and influences LONG-TERM POTENTIATION. It is also found in LUNG, TESTIS, OVARY, KIDNEY, and BREAST, and is expressed in many tumor types found in these tissues. It is often used as an immunohistochemical marker for MESOTHELIOMA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2014; was indexed under CALCIUM-BINDING PROTEINS, VITAMIN D-DEPENDENT 1987-2013
History Note: 2014
DeCS ID: 55313
Unique ID: D064032
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Calbindin 2 - Preferred
Concept UI M0579266
Scope note A calbindin protein that is differentially expressed in distinct populations of NEURONS throughout the vertebrate and invertebrate NERVOUS SYSTEM, and modulates intrinsic neuronal excitability and influences LONG-TERM POTENTIATION. It is also found in LUNG, TESTIS, OVARY, KIDNEY, and BREAST, and is expressed in many tumor types found in these tissues. It is often used as an immunohistochemical marker for MESOTHELIOMA.
Preferred term Calbindin 2
Entry term(s) Calretinin



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