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Descriptor English: CRISPR-Cas Systems
Descriptor Spanish: Sistemas CRISPR-Cas
Descriptor sistemas CRISPR-Cas
Scope note: Mecanismos adaptativos de defensa frente a los virus, en archaea y bacterias, que se basan en matrices de repetición de ADN denominados REPETICIONES PALINDRÓMICAS CORTAS AGRUPADAS REGULARMENTE INTERESPACIADAS (elementos CRISPR) que funcionan en conjunción con las PROTEÍNAS ASOCIADAS A CRISPR (proteínas Cas). Se han distinguido varios tipos, como son el Tipo I, Tipo II y Tipo III, atendiendo a los motivos firma de las PROTEÍNAS ASOCIADAS A CRISPR.
Descriptor Portuguese: Sistemas CRISPR-Cas
Descriptor French: Systèmes CRISPR-Cas
Entry term(s): CRISPR Cas Systems
CRISPR-Cas System
System, CRISPR-Cas
Systems, CRISPR-Cas
Tree number(s): G05.308.203.374.394
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064113
Scope note: Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR elements) that function in conjunction with CRISPR-ASSOCIATED PROTEINS (Cas proteins). Several types have been distinguished, including Type I, Type II, and Type III, based on signature motifs of CRISPR-ASSOCIATED PROTEINS.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Public MeSH Note: 2014
History Note: 2014
Related: CRISPR-Associated Protein 9 MeSH
Gene Editing MeSH
DeCS ID: 55391
Unique ID: D064113
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2018/01/16
CRISPR-Cas Systems - Preferred
Concept UI M0579709
Scope note Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR elements) that function in conjunction with CRISPR-ASSOCIATED PROTEINS (Cas proteins). Several types have been distinguished, including Type I, Type II, and Type III, based on signature motifs of CRISPR-ASSOCIATED PROTEINS.
Preferred term CRISPR-Cas Systems
Entry term(s) CRISPR Cas Systems
CRISPR-Cas System
System, CRISPR-Cas
Systems, CRISPR-Cas



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