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Descriptor English: Fingolimod Hydrochloride
Descriptor Spanish: Clorhidrato de Fingolimod
Descriptor clorhidrato de fingolimod
Entry term(s) fingolimod
Scope note: Un esfingosina-derivada y un AGENTE INMUNOSUPRESOR que bloquea la migración y el establecimiento de los LINFOCITOS para el SISTEMA NERVIOSO CENTRAL a través de su acción sobre los RECEPTORES DE LA ESFINGOSINA 1-FOSFATO. Se utiliza en el tratamiento de la ESCLEROSIS MÚLTIPLE.
Descriptor Portuguese: Cloridrato de Fingolimode
Descriptor French: Chlorhydrate de fingolimod
Entry term(s): 2-Amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol hydrochloride
FTY 720
FTY-720
FTY720
Fingolimod
Gilenia
Gilenya
Tree number(s): D02.033.100.700.350
D02.033.455.706.431
D02.092.063.700.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068876
Scope note: A sphingosine-derivative and IMMUNOSUPPRESSIVE AGENT that blocks the migration and homing of LYMPHOCYTES to the CENTRAL NERVOUS SYSTEM through its action on SPHINGOSINE 1-PHOSPHATE RECEPTORS. It is used in the treatment of MULTIPLE SCLEROSIS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Immunosuppressive Agents
Registry Number: G926EC510T
Public MeSH Note: 2016; FINGOLIMOD HYDROCHLORIDE was indexed under PROPYLENE GLYCOLS and SPHINGOSINE 1996-2015
History Note: 2016 (1996)
DeCS ID: 55866
Unique ID: D000068876
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/06
Revision Date: 2015/07/02
Fingolimod Hydrochloride - Preferred
Concept UI M0259274
Scope note A sphingosine-derivative and IMMUNOSUPPRESSIVE AGENT that blocks the migration and homing of LYMPHOCYTES to the CENTRAL NERVOUS SYSTEM through its action on SPHINGOSINE 1-PHOSPHATE RECEPTORS. It is used in the treatment of MULTIPLE SCLEROSIS.
Preferred term Fingolimod Hydrochloride
Entry term(s) 2-Amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol hydrochloride
FTY-720 - Narrower
Concept UI M0521995
Preferred term FTY-720
Entry term(s) FTY 720
FTY720
Gilenya - Narrower
Concept UI M0587375
Preferred term Gilenya
Entry term(s) Gilenia
Fingolimod - Broader
Concept UI M0259277
Preferred term Fingolimod



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