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Descriptor English: Pregabalin
Descriptor Spanish: Pregabalina
Descriptor pregabalina
Scope note: Derivado del ácido gamma-aminobutírico (GABA) que funciona como BLOQUEADOR DE LOS CANALES DE CALCIO y se utiliza como un ANTICONVULSIVANTE y como ANSIOLÍTICO. También se utiliza como un ANALGÉSICO en el tratamiento del DOLOR NEUROPÁTICO y FIBROMIALGIA.
Descriptor Portuguese: Pregabalina
Descriptor French: Prégabaline
Entry term(s): (R-)-3-isobutyl GABA
(S)-3-(aminomethyl)-5-methylhexanoic acid
(S+)-3-isobutyl GABA
1008, CI
3 isobutyl GABA
3-(aminomethyl)-5-methylhexanoic acid
3-isobutyl GABA
CI 1008
CI-1008
CI1008
GABA, 3-isobutyl
Lyrica
Tree number(s): D02.241.081.114.500.350.500
D12.125.190.350.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069583
Scope note: A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Analgesics
Anticonvulsants
Calcium Channel Blockers
Anti-Anxiety Agents
Registry Number: 55JG375S6M
Public MeSH Note: 2016; PREGABALIN was indexed under GAMMA-AMINOBUTYRIC ACID 1993-2015
History Note: 2016 (1993)
DeCS ID: 55884
Unique ID: D000069583
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2015/06/26
Pregabalin - Preferred
Concept UI M0214473
Scope note A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.
Preferred term Pregabalin
Entry term(s) (R-)-3-isobutyl GABA
(S)-3-(aminomethyl)-5-methylhexanoic acid
(S+)-3-isobutyl GABA
3 isobutyl GABA
3-(aminomethyl)-5-methylhexanoic acid
3-isobutyl GABA
GABA, 3-isobutyl
Lyrica - Narrower
Concept UI M0486135
Preferred term Lyrica
CI 1008 - Narrower
Concept UI M0259583
Preferred term CI 1008
Entry term(s) 1008, CI
CI-1008
CI1008



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