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Descriptor English: Tenofovir
Descriptor Spanish: Tenofovir
Descriptor tenofovir
Scope note: Análogo de la adenina, INHIBIDOR DE LA TRANSCRIPTASA INVERSA, con actividad antiviral contra el VIH-1 y la HEPATITIS B. Es usado para tratar las INFECCIONES POR VIH y HEPATITIS CRÓNICA B, en combinación con otros ANTIVIRALES, debido al surgimiento de la RESISTENCIA A ANTIVIRALES cuando se utiliza solo.
Descriptor Portuguese: Tenofovir
Descriptor French: Ténofovir
Entry term(s): (R)-9-(2-phosphonylmethoxypropyl)adenine
9-(2-Phosphonomethoxypropyl)adenine
9-(2-Phosphonylmethoxypropyl)adenine
9-(2-Phosphonylmethoxypropyl)adenine, (+-)-isomer
9-(2-Phosphonylmethoxypropyl)adenine, (R)-isomer - T357098
9-(2-Phosphonylmethoxypropyl)adenine, (S)-isomer
9-PMPA (tenofovir)
Disoproxil Fumarate, Tenofovir
Disoproxil, Tenofovir
Fumarate, Tenofovir Disoproxil
Tenofovir Disoproxil
Tenofovir Disoproxil Fumarate
Viread
Tree number(s): D02.705.429.906
D03.633.100.759.138.881
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068698
Scope note: An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antiviral Agents
Reverse Transcriptase Inhibitors
Anti-HIV Agents
Registry Number: 99YXE507IL
Public MeSH Note: 2016; TENOFOVIR DIDOPROXIL was indexed under ORGANOPHOSPHONATES 2004-2015, ADENINE 2004-2015, and under ORGANOPHOSPHOROUS COMPOUNDS 2001-2004
History Note: 2016 (2001)
DeCS ID: 55900
Unique ID: D000068698
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/09
Revision Date: 2016/07/05
Tenofovir - Preferred
Concept UI M0254881
Scope note An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.
Preferred term Tenofovir
Entry term(s) 9-(2-Phosphonomethoxypropyl)adenine
9-(2-Phosphonylmethoxypropyl)adenine
9-PMPA (tenofovir)
9-(2-Phosphonylmethoxypropyl)adenine, (S)-isomer - Narrower
Concept UI M0327097
Preferred term 9-(2-Phosphonylmethoxypropyl)adenine, (S)-isomer
9-(2-Phosphonylmethoxypropyl)adenine, (+-)-isomer - Narrower
Concept UI M0327096
Preferred term 9-(2-Phosphonylmethoxypropyl)adenine, (+-)-isomer
Tenofovir Disoproxil Fumarate - Narrower
Concept UI M0407969
Preferred term Tenofovir Disoproxil Fumarate
Entry term(s) Disoproxil Fumarate, Tenofovir
Fumarate, Tenofovir Disoproxil
Tenofovir Disoproxil - Narrower
Concept UI M000613540
Preferred term Tenofovir Disoproxil
Entry term(s) Disoproxil, Tenofovir
9-(2-Phosphonylmethoxypropyl)adenine, (R)-isomer - T357098 - Narrower
Concept UI M0327098
Preferred term 9-(2-Phosphonylmethoxypropyl)adenine, (R)-isomer - T357098
Entry term(s) (R)-9-(2-phosphonylmethoxypropyl)adenine
Viread - Narrower
Concept UI M0407970
Preferred term Viread



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