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Descriptor English: Lubiprostone
Descriptor Spanish: Lubiprostona
Descriptor lubiprostona
Scope note: Miembro de una clase de ácidos grasos bicíclicos de compuestos derivados de la PROSTAGLANDINA E1 que participa en la activación de los canales de cloruro.
Descriptor Portuguese: Lubiprostona
Descriptor French: Lubiprostone
Entry term(s): 0211, RU
0211, SPI
Amitiza
Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11alpha)-
RU 0211
RU-0211
RU0211
SPI 0211
SPI-0211
SPI0211
Tree number(s): D10.251.355.325.050.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068238
Scope note: Member of a bicyclic fatty acid class of compounds derived from PROSTAGLANDIN E1 involved in chloride channel gating.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Chloride Channel Agonists
Registry Number: 7662KG2R6K
CAS Type 1 Name: 7-((1R,4R,6R,9R)-4-(1,1-difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo(4.3.0)non-9-yl)heptanoic acid
Public MeSH Note: 2016; LUBIPROSTONE was indexed under ALPROSTADIL 2005-2015
History Note: 2016 (2005)
DeCS ID: 55962
Unique ID: D000068238
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/10
Revision Date: 2015/07/09
Lubiprostone - Preferred
Concept UI M0493211
Scope note Member of a bicyclic fatty acid class of compounds derived from PROSTAGLANDIN E1 involved in chloride channel gating.
Preferred term Lubiprostone
Entry term(s) Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11alpha)-
RU 0211 - Narrower
Concept UI M0493212
Preferred term RU 0211
Entry term(s) 0211, RU
RU-0211
RU0211
Amitiza - Broader
Concept UI M0497992
Preferred term Amitiza
SPI 0211 - Narrower
Concept UI M0493213
Preferred term SPI 0211
Entry term(s) 0211, SPI
SPI-0211
SPI0211



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