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Descriptor English: Autophagosomes
Descriptor Spanish: Autofagosomas
Descriptor autofagosomas
Entry term(s) autofagosoma
fagóforos
vacuola autofágica
Scope note: Estructuras grandes y esféricas, de doble capa, que participan en la AUTOFAGIA englobando componentes intracelulares tales como ORGÁNULOS o patógenos. Su membrana externa se fusiona a continuación con los LISOSOMAS (formando el AUTOLISOSOMA) y la membrana interna y el contenido son digeridos por las HIDROLASAS lisosomales.
Descriptor Portuguese: Autofagossomos
Descriptor French: Autophagosomes
Entry term(s): Autophagosome
Phagophore
Phagophores
Tree number(s): A11.284.430.214.190.875.190.700.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071182
Scope note: Large spherical double-layered structures which function in AUTOPHAGY to engulf intracellular components such as ORGANELLES or pathogens. Their outer membrane then fuses with the LYSOSOME (forming the AUTOLYSOSOME) and the inner membrane and contents are digested by lysosomal HYDROLASES.
Allowable Qualifiers: CH chemistry
CL classification
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Autophagy (1976-2016)
Phagocytosis (1975-2016)
Phagosomes (1986-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56272
Unique ID: D000071182
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2020/06/09
Autophagosomes - Preferred
Concept UI M000613429
Scope note Large spherical double-layered structures which function in AUTOPHAGY to engulf intracellular components such as ORGANELLES or pathogens. Their outer membrane then fuses with the LYSOSOME (forming the AUTOLYSOSOME) and the inner membrane and contents are digested by lysosomal HYDROLASES.
Preferred term Autophagosomes
Entry term(s) Autophagosome
Phagophores - Related but not broader or narrower
Concept UI M000655218
Scope note Double-membrane, cup-shaped structures destined to become autophagosomes.
Preferred term Phagophores
Entry term(s) Phagophore



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