Descriptor English: | DNA Ligase ATP | ||||||
Descriptor Spanish: |
ADN Ligasa (ATP)
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Descriptor Portuguese: | DNA Ligase Dependente de ATP | ||||||
Descriptor French: | DNA ligase ATP | ||||||
Entry term(s): |
ATP, DNA Ligase ATP, Polydeoxyribonucleotide Synthase ATP-Dependent DNA Ligase ATP-Dependent DNA Ligases DNA Ligase I DNA Ligase II DNA Ligase III DNA Ligase IIIalpha DNA Ligase IV DNA Ligases, ATP Dependent DNA Ligases, ATP-Dependent IIIalpha, DNA Ligase LIGIIIalpha Protein Ligase ATP, DNA Ligase I, DNA Ligase II, DNA Ligase III, DNA Ligase IIIalpha, DNA Ligase IV, DNA Ligases, ATP-Dependent DNA Polydeoxyribonucleotide Synthase ATP Synthase ATP, Polydeoxyribonucleotide |
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Tree number(s): |
D08.811.074.500.500 D08.811.464.754.600.500 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000072481 | ||||||
Scope note: | ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 6.5.1.1 | ||||||
Public MeSH Note: | 2018; DNA LIGASE (ATP) was indexed under DNA LIGASES 1986-2016; DNA LIGASE IIIALPHA was indexed under DNA LIGASES 1991-2017 |
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History Note: | 2018 (1986) |
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DeCS ID: | 56464 | ||||||
Unique ID: | D000072481 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2017/01/01 | ||||||
Date of Entry: | 2016/07/08 | ||||||
Revision Date: | 2017/06/29 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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DNA Ligase ATP
- Preferred
DNA Ligase I
- Narrower
DNA Ligase IIIalpha
- Narrower
DNA Ligase IV
- Narrower
DNA Ligase III
- Narrower
Concept UI |
M000619283 |
Scope note | ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent. |
Preferred term | DNA Ligase ATP |
Entry term(s) |
ATP, DNA Ligase ATP, Polydeoxyribonucleotide Synthase ATP-Dependent DNA Ligase ATP-Dependent DNA Ligases DNA Ligases, ATP Dependent DNA Ligases, ATP-Dependent Ligase ATP, DNA Ligases, ATP-Dependent DNA Polydeoxyribonucleotide Synthase ATP Synthase ATP, Polydeoxyribonucleotide |
Concept UI |
M0472159 |
Preferred term | DNA Ligase I |
Entry term(s) |
Ligase I, DNA |
Concept UI |
M0480519 |
Preferred term | DNA Ligase IIIalpha |
Entry term(s) |
IIIalpha, DNA Ligase LIGIIIalpha Protein Ligase IIIalpha, DNA |
Concept UI |
M0472161 |
Preferred term | DNA Ligase IV |
Entry term(s) |
Ligase IV, DNA |
Concept UI |
M000618783 |
Preferred term | DNA Ligase III |
Entry term(s) |
DNA Ligase II Ligase II, DNA Ligase III, DNA |
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