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Descriptor English: Ligases
Descriptor Spanish: Ligasas
Descriptor ligasas
Entry term(s) ligasa
sintasa
sintasas
sintetasa
sintetasas
Scope note: Clase de enzimas que catalizan la formación de un enlace entre dos moléculas de sustrato, proceso que se acopla con la hidrólisis de un enlace pirofosfato del ATP o de un donante de energía similar. (Dorland, 28th ed) EC 6.
Descriptor Portuguese: Ligases
Descriptor French: Ligases
Entry term(s): Ligase
Synthetase
Synthetases
Tree number(s): D08.811.464
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008025
Scope note: A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 6.-
Public MeSH Note: CARBOXYLASES was see under CARBOXY-LYASES & LIGASES 1964-74, was heading 1963; CARBAMYL PHOSPHATE SYNTHASE (AMMONIA) & CARBAMYL PHOSPHATE SYNTHASE (GLUTAMINE) were see under PHOSPHOTRANSFERASES, ATP 1975-80
Online Note: use LIGASES & CARBOXY-LYASES to search CARBOXYLASES 1966-74
History Note: CARBOXYLASES was see under CARBOXY-LYASES & LIGASES 1964-74, was heading 1963
DeCS ID: 8201
Unique ID: D008025
NLM Classification: QU 138
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1963/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Ligases - Preferred
Concept UI M0012509
Scope note A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6.
Preferred term Ligases
Entry term(s) Ligase
Synthetase
Synthetases



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